CAS 36282-26-5

2-Bromo-4-fluorobenzonitrile

Description:

2-Bromo-4-fluorobenzonitrile is an organic compound characterized by the presence of both bromine and fluorine substituents on a benzene ring, along with a nitrile functional group. Its molecular structure consists of a benzene ring with a bromine atom at the second position and a fluorine atom at the fourth position, with a cyano group (-C≡N) attached to the benzene. This compound is typically a colorless to pale yellow solid and is known for its moderate solubility in organic solvents. It exhibits properties typical of halogenated aromatic compounds, such as increased reactivity in electrophilic substitution reactions. The presence of the nitrile group contributes to its polarity and can influence its reactivity, making it useful in various synthetic applications, including pharmaceuticals and agrochemicals. Additionally, 2-Bromo-4-fluorobenzonitrile can serve as an important intermediate in organic synthesis, particularly in the development of more complex molecules. Safety precautions should be observed when handling this compound due to its potential toxicity and environmental impact.

Formula: C₇H₃BrFN

InChI: InChI=1S/C7H3BrFN/c8-7-3-6(9)2-1-5(7)4-10/h1-3H

InChI key: InChIKey=MNNDREXLRLDWEY-UHFFFAOYSA-N

SMILES: C(#N)C1=C(Br)C=C(F)C=C1

Synonyms:

• 4-Fluoro-2-bromobenzonitrile
• Benzonitrile,2-bromo-4-fluoro-
• 2-Bromo-4-fluorobenzonitrile

2-Bromo-4-fluorobenzonitrile

CAS: 36282-26-5

Formula: C₇H₃BrFN

Purity: >98.0%(GC)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 200.01

Ref: 3B-B2744

2-Bromo-4-fluorobenzonitrile, 98%

CAS: 36282-26-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₃BrFN

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder or fused/lumpy solid, White to pale cream

Molecular weight: 200.01

Ref: 02-L20115

2-bromo-4-fluorobenzonitrile

CAS: 36282-26-5

Formula: C₇H₃BrFN

Purity: 95%

Color and Shape: Solid

Molecular weight: 200.0078

Ref: IN-DA003GO8

2-Bromo-4-fluorobenzonitrile

CAS: 36282-26-5

2-Bromo-4-fluorobenzonitrile

Formula: C₇H₃BrFN

Purity: 98%

Color and Shape: solid

Molecular weight: 200.01g/mol

Ref: 54-PC7371

2-Bromo-4-fluorobenzonitrile

CAS: 36282-26-5

2-Bromo-4-fluorobenzonitrile is a chemical compound that has the molecular formula C6H5BrF2. It is a competitive inhibitor of chaperones. This molecule also has structural isomers, including 2-bromo-4-fluoroaniline and 2,4-dichlorobenzonitrile. The clinical development of this drug for cancer treatment has been halted due to toxic effects on the heart. However, it was shown in animal studies that 2-bromo-4-fluorobenzonitrile can inhibit the growth of tumour cells in a dose dependent manner with nanomolar concentrations. It is believed that these properties are due to its ability to bind to type 1 receptors and inhibit surfactant sodium dodecyl (SDS) fluorescence.

Formula: C₇H₃BrFN

Purity: Min. 95%

Molecular weight: 200.01 g/mol

Ref: 3D-FB50744

2-Bromo-4-fluorobenzonitrile

CAS: 36282-26-5

Formula: C₇H₃BrFN

Purity: 95%

Color and Shape: Solid

Molecular weight: 200.01

Ref: 10-F013212