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CAS 36282-40-3

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3-methoxyphenylmagnesium bromide

Description:
3-Methoxyphenylmagnesium bromide is an organomagnesium compound, specifically a Grignard reagent, characterized by its reactivity and utility in organic synthesis. It features a phenyl group substituted with a methoxy group at the meta position, which enhances its nucleophilicity. This compound is typically prepared by reacting 3-methoxyphenyl bromide with magnesium in an anhydrous ether solvent, such as diethyl ether or tetrahydrofuran. As a Grignard reagent, it is highly reactive towards electrophiles, making it valuable for forming carbon-carbon bonds in various synthetic pathways, including the synthesis of alcohols, ketones, and other functional groups. However, it is sensitive to moisture and air, requiring careful handling under inert conditions to prevent decomposition. The presence of the methoxy group can influence the reactivity and selectivity of the reactions it participates in, often leading to regioselective outcomes. Overall, 3-methoxyphenylmagnesium bromide is a significant reagent in the field of synthetic organic chemistry.
Formula:C7H7BrMgO
InChI:InChI=1/C7H7O.BrH.Mg/c1-8-7-5-3-2-4-6-7;;/h2-3,5-6H,1H3;1H;/q;;+1/p-1/rC7H7BrMgO/c1-10-7-4-2-3-6(5-7)9-8/h2-5H,1H3
SMILES:COc1ccccc1.Br.[Mg]
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