CAS 3637-10-3: 1,4-Dihydroxy-2,2,6,6-tetramethylpiperidine

Description: 1,4-Dihydroxy-2,2,6,6-tetramethylpiperidine, commonly referred to as TEMPOL, is a stable free radical compound known for its antioxidant properties. It features a piperidine ring with two hydroxyl groups at the 1 and 4 positions and four methyl groups at the 2 and 6 positions, contributing to its steric bulk and stability. TEMPOL is soluble in water and various organic solvents, making it versatile for different applications. Its radical nature allows it to scavenge reactive oxygen species, which is beneficial in biological systems and potential therapeutic contexts. Additionally, TEMPOL has been studied for its role in reducing oxidative stress, protecting cells from damage, and its potential use in various fields, including biochemistry and medicine. The compound is also noted for its ability to cross biological membranes, which enhances its utility in pharmacological studies. Overall, TEMPOL is a significant compound in research related to oxidative stress and cellular protection.

Formula: C₉H₁₉NO₂

InChI: InChI=1S/C9H19NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11-12H,5-6H2,1-4H3

InChI key: InChIKey=CSGAUKGQUCHWDP-UHFFFAOYSA-N

SMILES: ON1C(C)(C)CC(O)CC1(C)C

Synonyms:

• 1,4-Dihydroxy-2,2,6,6-tetramethylpiperidine
• 1-Hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidine
• 1-Hydroxy-2,2,6,6-tetramethyl-4-piperidinol
• 4-Hydroxy-2,2,6,6-tetramethyl-N-hydroxypiperidine
• Ot 674
• Tempol H
• Tolh
• 4-Piperidinol, 1-hydroxy-2,2,6,6-tetramethyl-

Tempol H

CAS: 3637-10-3

• Formula: C₉H₁₉NO
• Molecular weight: 173.26