CAS 364-62-5
:Metoclopramide
Description:
Metoclopramide is a medication primarily used to treat nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. It acts as a dopamine receptor antagonist, enhancing gastrointestinal motility and accelerating gastric emptying. The chemical formula of metoclopramide is C14H22ClN3O2S, and it features a piperazine ring, which contributes to its pharmacological activity. This compound is typically administered orally or intravenously and is known for its ability to cross the blood-brain barrier, which can lead to central nervous system side effects such as drowsiness or restlessness. Metoclopramide is also utilized in the management of gastroesophageal reflux disease (GERD) and to facilitate certain diagnostic procedures. Its safety profile includes potential adverse effects, including tardive dyskinesia with long-term use, necessitating careful monitoring. The CAS number 364-62-5 uniquely identifies this substance in chemical databases, aiding in its regulation and research. Overall, metoclopramide is a versatile agent in the field of gastroenterology and anesthesiology.
Formula:C14H22ClN3O2
InChI:InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)
InChI key:InChIKey=TTWJBBZEZQICBI-UHFFFAOYSA-N
SMILES:C(NCCN(CC)CC)(=O)C1=C(OC)C=C(N)C(Cl)=C1
Synonyms:- 2-Methoxy-4-amino-5-chloro-N,N-dimethylaminoethylbenzamide
- 2-Methoxy-5-chloroprocainamide
- 4-Amino-5-chloro-2-methoxy-N-(β-diethylaminoethyl)benzamide
- 4-Amino-5-chloro-N-(2' (diethylamino) ethyl)-o-anisic acid amide
- 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
- 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-o-anisamide
- 4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide
- 5-Chloro-2-methoxyprocainamide
- Afipran
- Ahr 3070C
- Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-
- Clopromate
- Del 1267
- Draclamid
- Emperal
- Eucil
- Gastrese
- Gastro-Timelets
- Gastro-tablinen
- Gastrobid
- Gastromax
- Gastrosil
- Gastrotem
- MCP-ratiopharm
- Macperan
- Maxeran
- Meclopran
- Metamide
- Methochlopramide
- Metochlopramide
- Metoclol
- Metoclopramid
- Metoclopramida
- Metoclopramide anhydrous
- Metocobil
- Metramid
- Moriperan
- N-(2-Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide
- N-(Diethylaminoethyl)-2-methoxy-4-amino-5-chlorbenzamide
- N-(Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide
- N-[2-(Diethylamino)ethyl]-4-amino-5-chloro-2-methoxybenzamide
- Orpamid
- Parmid
- Plasil
- Plasil (pharmaceutical)
- Primperan
- Regla
- Reliveran
- o-Anisamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-
- Metaclopramide
- Metoclopranide
- Anisamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-
- 4-amino-5-chloro-n-(2-(diethylamino)ethyl)-n-anisamid
- 4-amino-5-chloro-n-(2-(diethylamino)ethyl)-2-methoxy-benzamid
- Metaclopromide
- 4-Amino-5-Cholo-N-[(2-diethylamino)ethyl]-2-methyloxy-benzamide
- Methoclopramide
- 4-amino-5-chloro-n-(2-(diethylamino)ethyl)-o-anisamid
- del1267
- See more synonyms
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Metoclopramide
CAS:Formula:C14H22ClN3O2Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:299.80METOCLOPRAMIDE CRS
CAS:METOCLOPRAMIDE CRSFormula:C14H22ClN3O2Color and Shape:Fine Powder. White. Powder.Molecular weight:299.79644-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
CAS:Formula:C14H22ClN3O2Purity:98%Color and Shape:SolidMolecular weight:299.7964Metoclopramide (Standard)
CAS:Metoclopramide (Standard) is the standard substance of Metoclopramide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is the antiemetic drug of choice in pregnant women. Findings provide reassurance regarding the safety of metoclopramide for the fetus when the drug is given to women to relieve nausea and vomiting during pregnancy. Evidence also supports its use for gastroparesis (poor stomach emptying) and gastroesophageal reflux disease. It appears to bind to dopamine D2 receptors where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist/ 5-HT4 receptor agonist.Formula:C14H22ClN3O2Molecular weight:299.796Metoclopramide
CAS:Applications Metoclopramide is a treatment of choice of post-operative nausea and vomiting (PONV) prophylaxis.
References Agarwal, A., et al.: World J. Pharm. Res., 5, 1238-1245 (2016)Formula:C14H22ClN3O2Color and Shape:NeatMolecular weight:299.8Metoclopramide
CAS:Metoclopramide: dopamine D2 antagonist, treats nausea, vomiting, gastroparesis, GERD; safe for pregnancy.Formula:C14H22ClN3O2Purity:99.75%Color and Shape:White SolidMolecular weight:299.796Metoclopramide in Acetonitrile
CAS:AcetonitrileFormula:C14H22ClN3O2Color and Shape:SolidMolecular weight:299.79Metoclopramide base
CAS:Dopamine (D2) receptor antagonist
Formula:C14H22ClN3O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:299.8 g/mol












