CAS 3646-28-4

Estr-4-en-17-one

Description:

Estr-4-en-17-one, also known as estrone, is a naturally occurring estrogen steroid hormone. It is characterized by its steroid structure, which includes a phenolic A-ring and a ketone group at the C17 position. Estrone plays a crucial role in the regulation of the female reproductive system and is involved in various physiological processes, including the menstrual cycle and pregnancy. As a member of the estrogen family, it exhibits biological activity by binding to estrogen receptors, influencing gene expression and cellular function. Estrone is typically found in the ovaries, adrenal glands, and peripheral tissues, and its levels fluctuate throughout the menstrual cycle. In terms of physical properties, estrone is a white crystalline solid that is soluble in organic solvents but has limited solubility in water. It is also important in clinical settings, as its levels can be indicative of certain health conditions, including hormonal imbalances and menopause. Overall, estrone is a vital hormone with significant implications for reproductive health and endocrine function.

Formula: C₁₈H₂₆O

InChI: InChI=1S/C18H26O/c1-18-11-10-14-13-5-3-2-4-12(13)6-7-15(14)16(18)8-9-17(18)19/h4,13-16H,2-3,5-11H2,1H3/t13-,14+,15+,16-,18-/m0/s1

InChI key: InChIKey=OLYAEHZZXXLNQQ-QXUSFIETSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@@]4(C(CC3)=CCCC4)[H])(CC1)[H])[H])(CCC2=O)[H]

Synonyms:

• 2,3,8,9,10-Pentachloro-6-methyl-6H-dibenzo[c,e][1,2]thiazine 5,5-dioxide
• 6H-Dibenzo[c,e][1,2]thiazine, 2,3,8,9,10-pentachloro-6-methyl-, 5,5-dioxide
• Estr-4-En-17-One
• Estrenone
• Oestr-4-en-17-one

Allylestrenol Impurity 1

CAS: 3646-28-4

Formula: C₁₈H₂₆O

Color and Shape: White To Off-White Solid

Molecular weight: 258.41

Ref: 4Z-A-180002

Estr-4-en-17-one

Controlled Product

CAS: 3646-28-4

Applications Estr-4-en-17-one, is an impurity of Allylestrenol. It can be used in the synthesis of Ethylestrenol (E917830), an anabolic steroid.
References Van Puymbroeck, M. et al.: J. Chrom. B Biomed. Sci. Appl., 728, 217 (1999); Wekhe, S.N. et al.: J. Appl. Animal Res., 5, 119 (1994);

Formula: C₁₈H₂₆O

Color and Shape: Neat

Molecular weight: 258.4

Ref: TR-E889085

Estr-4-en-17-one

Controlled Product

CAS: 3646-28-4

Estr-4-en-17-one is a medicinal compound that has shown promising results as an anticancer agent. It has been found to inhibit the growth of cancer cells in Chinese hamster ovary (CHO) cells and human leukemia cells. Estr-4-en-17-one works by inhibiting protein kinases, which are enzymes that play a key role in cell cycle regulation and apoptosis. This compound also acts as a tumor inhibitor by inducing apoptosis in cancer cells. Estr-4-en-17-one is excreted in urine, making it a potential biomarker for detecting certain types of cancers. With its potent anticancer properties, Estr-4-en-17-one shows great promise as a potential treatment for various forms of cancer.

Formula: C₁₈H₂₆O

Purity: Min. 95%

Molecular weight: 258.4 g/mol

Ref: 3D-DAA64628

Allylestrenol Impurity A

CAS: 3646-28-4

Formula: C₁₈H₂₆O

Molecular weight: 258.4

Ref: ST-EA-CP-A52001