CAS 36507-48-9

2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-

Description:

2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]- is a chemical compound characterized by its complex structure, which includes a propanol backbone, a cyclopentylphenoxy group, and a tert-butylamino substituent. This compound is likely to exhibit properties typical of alcohols, such as being a polar solvent and having the ability to form hydrogen bonds due to the presence of the hydroxyl (-OH) group. The presence of the cyclopentyl and phenoxy groups may contribute to its hydrophobic characteristics, influencing its solubility in organic solvents. Additionally, the tert-butylamino group can impart basicity and may affect the compound's reactivity and interaction with biological systems. The molecular structure suggests potential applications in pharmaceuticals or as a chemical intermediate, although specific applications would depend on further studies of its biological activity and stability. Safety data and handling precautions should be consulted due to the potential hazards associated with chemical substances.

Formula: C₁₈H₂₉NO₂

InChI: InChI=1S/C18H29NO2/c1-18(2,3)19-12-15(20)13-21-17-11-7-6-10-16(17)14-8-4-5-9-14/h6-7,10-11,14-15,19-20H,4-5,8-9,12-13H2,1-3H3

InChI key: InChIKey=KQXKVJAGOJTNJS-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)(C)C)O)C1=C(C=CC=C1)C2CCCC2

Synonyms:

• (.+-.)-Isopenbutolol
• (.+-.)-Penbutolol
• 1-(2-Cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol
• 1-(Terc-Butilamino)-3-(O-Ciclopentilfenoxi)Propan-2-Ol
• 1-(Tert-Butylamino)-3-(O-Cyclopentylphenoxy)Propan-2-Ol
• 1-(Tert-Butylamino)-3-(O-Cyclopentylphenoxy)Propane-2-Ol
• 2-Propanol, 1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)-
• (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol
• 2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-

rac Penbutolol

CAS: 36507-48-9

Applications A β-adrenoceptor antagonist. Antihypertensive.
References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994), Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003),

Formula: C₁₈H₂₉NO₂

Color and Shape: Off-White

Molecular weight: 291.43

Ref: TR-P220500

rac Penbutolol

CAS: 36507-48-9

Rac Penbutolol is a beta-adrenergic blocker that has been shown to be effective in the treatment of hypertension, angina pectoris, and arrhythmia. Rac Penbutolol is used for the treatment of hypertension and angina pectoris by blocking the effects of catecholamines on the heart and blood vessels. The drug also decreases peripheral vascular resistance, which lowers blood pressure and reduces cardiac workload. Rac Penbutolol has been shown to be effective in treating atrial fibrillation by slowing conduction through the heart. This drug binds to beta-adrenergic receptors in the heart muscle, causing relaxation of the muscle fibers and preventing them from contracting. Rac Penbutolol can be detected in urine samples using monoclonal antibodies, which are used to identify specific proteins or other substances in a sample. The detection time for rac Penbutolol is typically four days after ingestion when it is taken orally with food. Rac Penbut

Formula: C₁₈H₂₉NO₂

Purity: Min. 95%

Molecular weight: 291.4 g/mol

Ref: 3D-LBA50748

(±)-Penbutolol

CAS: 36507-48-9

(±)-Penbutolol ((Rac)-Penbutolol) is the racemic form of Penbutolol. It acts as an orally active β-adrenergic receptor antagonist. (±)-Penbutolol mitigates the tachycardia induced by exercise, reduces the increase in peak expiratory flow rate (PEFR) caused by physical activity, and decreases plasma renin activity (PRA) at rest. The peak plasma concentration of this compound is achieved one hour after oral administration, with a half-life of 4.5 hours, and it is metabolized into active metabolites in the body. This compound is utilized in research related to cardiovascular diseases.

Formula: C₁₈H₂₉NO₂

Color and Shape: Solid

Molecular weight: 291.43

Ref: TM-T201472