CAS 365441-71-0

Poly(oxy-1,2-ethanediyl), α-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-ω-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]-

Description:

Poly(oxy-1,2-ethanediyl), α-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-ω-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]- is a complex synthetic polymer characterized by its polyether backbone and functional groups that enhance its solubility and reactivity. This substance typically exhibits properties such as biocompatibility, making it suitable for pharmaceutical applications, particularly in drug delivery systems. The presence of various functional groups, including pyrrolidinyl and thieno[3,4-d]imidazol moieties, suggests potential interactions with biological systems, which may facilitate targeted delivery or improved efficacy of therapeutic agents. Additionally, the polymer's structure may allow for modifications that can tailor its properties for specific applications, such as in the development of hydrogels or other advanced materials. Overall, this compound represents a versatile platform in medicinal chemistry and materials science, with implications for enhancing drug solubility and bioavailability.

Formula: (C₂H₄O)nC₁₉H₂₈N₄O₇S

InChI: InChI=1S/C21H32N4O8S/c26-16(4-2-1-3-15-20-14(13-34-15)23-21(30)24-20)22-8-10-32-12-11-31-9-7-19(29)33-25-17(27)5-6-18(25)28/h14-15,20H,1-13H2,(H,22,26)(H2,23,24,30)

InChI key: InChIKey=UCJSJBIJPAZUGU-UHFFFAOYSA-N

SMILES: C(CCCC(NCCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)C2C3C(CS2)NC(=O)N3

Synonyms:

• (+)-Biotin-PEG12-CH2CH2COONHS Ester
• EZ-Link NHS-PEG12-Biotin
• alpha-[3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-omega-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]-poly(oxy-1,2-ethanediyl)
• (+)-BIOTIN-PEG24-NHS ESTER
• Poly(oxy-1,2-ethanediyl), α-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-ω-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]-
• Biotin-PEG24-SPA
• NHS-PEO12-Biotin
• -NHS Ester
• Biotin-PEG12-NHS ester
• (+)-Biotin-PEG??-NHS Ester
• Biotin-PEG12-SPA
• Biotin-dPEG(24)-NHS
• Biotin-PEGn-NHS ester
• NHS-PEG12-Biotin
• NHS-dPEG???-biotin
• (+)-BIOTIN-PEG24-NHS ESTER;(+)-BIOTIN-PEG24-NHS ESTER
• 24
• (+)-Biotin-PEG

Biotin-PEG12-NHS ester

CAS: 365441-71-0

Formula: C₁₉H₂₈N₄O₇S

Purity: 95%

Color and Shape: Solid

Molecular weight: 456.5132

Ref: IN-DA00CILH

Biotin-PEG12-NHS

CAS: 365441-71-0

Biotin-PEG12-NHS is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Biotin-PEG12-NHS is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₄₁H₇₂N₄O₁₈S

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 941.09 g/mol

Ref: 3D-FB72909

EZ-Link NHS-PEG12-Biotin

Controlled Product

CAS: 365441-71-0

Stability Moisture Sensitive
Applications EZ-Link NHS-PEG12-Biotin is a reactant in the preparation of biotin-CTT54 ligands and multivalent PSMA inhibitor-guided streptavidin conjugates for targeting prostate cancer cells.
References Liu, T., et. al.: Bioorg. Med. Chem. Lett., 22, 3931 (2012)

Formula: C₁₉H₂₈N₄O₇S

Color and Shape: Neat

Molecular weight: 456.513

Ref: TR-N394010

NHS-dPEG®12 Biotin

CAS: 365441-71-0

NHS-dPEG®12 Biotin is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-dPEG®12 Biotin is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Purity: Min. 95%

Molecular weight: 941.09 g/mol

Ref: 3D-DPG-5703

m-dPEG®4-Lipoamide

CAS: 365441-71-0

m-dPEG®4-Lipoamide is a PEG molecule conjugated with a lipid moiety. m-dPEG®4-Lipoamide, conjugated to this lipid constituent, is very important especially in drug delivery and vaccine development as it helps improve the stability and circulation time of lipid nanoparticles (LNPs) and liposomes.

Formula: C₄₁H₇₂N₄O₁₈S

Purity: Min. 95%

Molecular weight: 941.09 g/mol

Ref: 3D-DPG-6156