CAS 366-93-8

1,4-Cyclohexanedimethanamine, N1,N4-bis[(2-chlorophenyl)methyl]-, hydrochloride (1:2), trans-

Description:

1,4-Cyclohexanedimethanamine, N1,N4-bis[(2-chlorophenyl)methyl]-, hydrochloride (1:2), trans- is a chemical compound characterized by its complex structure, which includes a cyclohexane ring with two amine groups and two 2-chlorobenzyl substituents. This compound is typically encountered as a hydrochloride salt, which enhances its solubility in water and facilitates its handling in various applications. The presence of the chlorophenyl groups contributes to its potential biological activity, making it of interest in medicinal chemistry and pharmacology. The trans configuration indicates the specific spatial arrangement of the substituents around the cyclohexane ring, which can influence the compound's reactivity and interaction with biological targets. As with many amines, it may exhibit basic properties and can participate in various chemical reactions, including alkylation and acylation. Safety data should be consulted, as compounds with halogenated aromatic groups can pose environmental and health risks. Overall, this compound's unique structure and properties make it a subject of interest in both research and industrial applications.

Formula: C₂₂H₂₈Cl₂N₂·2ClH

InChI: InChI=1/C22H28Cl2N2.2ClH/c23-21-7-3-1-5-19(21)15-25-13-17-9-11-18(12-10-17)14-26-16-20-6-2-4-8-22(20)24;;/h1-8,17-18,25-26H,9-16H2;2*1H/t17-,18-;;

InChI key: InChIKey=NRVIEWRSGDDWHP-PMXFUEHMNA-N

SMILES: C(NC[C@H]1CC[C@H](CNCC2=C(Cl)C=CC=C2)CC1)C3=C(Cl)C=CC=C3.Cl

Synonyms:

• N,N′-Bis(o-chlorobenzyl)-trans-1,4-cyclohexanebis(methylamine) dihydrochloride
• 1,4-Cyclohexanedimethanamine, N,N′-bis[(2-chlorophenyl)methyl]-, dihydrochloride, trans-
• 1,4-Cyclohexanedimethanamine, N1,N4-bis[(2-chlorophenyl)methyl]-, hydrochloride (1:2), trans-
• 1,4-Cyclohexanebis(methylamine), N,N′-bis(o-chlorobenzyl)-, dihydrochloride, trans-
• AY 9944
• trans-id
• TRANS-1,4-BIS(2-CHLOROBENZYLAMINOETHYL) CYCLOHEXANE DIHYDROCHLORIDE
• 4-cyclohexanedimethanamine,n,n’-bis((2-chlorophenyl)methyl)-dihydrochlor
• AY 9944 - CAS 366-93-8 - Calbiochem
• AY99442HCl
• trans1,4-bis(2-dichlorobenzylaminoethyl)cyclohexanedichlorhydrate
• trans-1,4-Bis(2-chlorobenzylaminomethyl)cyclohexane,dihydrochloride
• trans-n,n’-bis(2-chlorobenzyl)-1,4-cyclohexanebis(methylamine)dihydrochlorid
• AY 9944 DIHYDROCHLORIDE
• 1,4-BIS(2-CHLOROBENZYLAMINOMETHYL)CYCLOHEXANE DIHYDROCHLORIDE
• trans-1,4-Bis(2-Chlorobenzylamimomethyl)cyclohexane dihydrochloride
• TRANS-1,4-BIS(2-CHLOROBENZYLAMINOMETHYL)CYCLOHEXANE, 2HCL
• trans-N1,N4-Bis[(2-chlorophenyl)methyl]-1,4-cyclohexanedimethanamine Hydrochloride
• trans-n,n’-(1,4-cyclohexylenedimethylene)bis(2-chlorobenzylamine)dihydrochlo
• TRANS-N,N-BIS[2-CHLOROPHENYLMETHYL]-1,4-CYCLOHEXANEDIMETHANAMINE DIHYDROCHLORIDE
• 4-cyclohexanebis(methylamine),n,n’-bis(o-chlorobenzyl)-dihydrochloride
• (2-chlorobenzyl)-[[4-[[(2-chlorobenzyl)amino]methyl]cyclohexyl]methyl]amine dihydrochloride
• trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexanedihydrochloride
• N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine dihydrochloride
• 1,4-cyclohexanebis(methylamine),n,n’-bis(2-chlorobenzyl)-,dihydrochloride,(e

AY 9944

CAS: 366-93-8

AY 9944

Purity: ≥95%

Molecular weight: 464.3g/mol

Ref: 54-BUP16278

AY 9944

CAS: 366-93-8

AY 9944 inhibits DHCR7 enzyme (IC50=13 nM) and sterol isomerase, leading to hypocholesterolemia and 7DHC buildup.

Formula: C₂₂H₃₀Cl₄N₂

Purity: 98.92% - 99.65%

Color and Shape: Solid

Molecular weight: 464.3

Ref: TM-T14362