CAS 366-99-4

3-fluoro-P-anisidine

Description:

3-Fluoro-P-anisidine, also known as 3-fluoro-4-methoxyaniline, is an aromatic amine characterized by the presence of a fluorine atom and a methoxy group attached to a benzene ring. Its molecular structure features a fluorine substituent at the meta position relative to the amino group and a methoxy group at the para position. This compound is typically a solid at room temperature and is known for its moderate solubility in organic solvents. It exhibits properties typical of aromatic amines, including potential reactivity in electrophilic substitution reactions. The presence of the fluorine atom can influence the compound's electronic properties, potentially enhancing its reactivity compared to non-fluorinated analogs. 3-Fluoro-P-anisidine is utilized in various applications, including as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. As with many aromatic amines, it is important to handle this compound with care due to potential health hazards, including toxicity and environmental impact. Proper safety measures should be observed when working with this substance.

Formula: C₇H₈FNO

InChI: InChI=1/C7H8FNO/c1-10-7-3-2-5(9)4-6(7)8/h2-4H,9H2,1H3

SMILES: COc1ccc(cc1F)N

Synonyms:

• 3-Fluoro-4-methoxyaniline
• 4-Amino-2-fluoroanisol
• 3-Fluoro-4-anisidine
• 4-Amino-2-fluoroanisole

3-Fluoro-4-methoxyaniline, 98+%

CAS: 366-99-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₈FNO

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 141.15

Ref: 02-A18606

Benzenamine, 3-fluoro-4-methoxy-

CAS: 366-99-4

Formula: C₇H₈FNO

Purity: 96%

Color and Shape: Solid

Molecular weight: 141.1429

Ref: IN-DA00I797

3-Fluoro-4-methoxyaniline

CAS: 366-99-4

3-Fluoro-4-methoxyaniline

Formula: C₇H₈FNO

Purity: ≥95%

Color and Shape: brown solid

Molecular weight: 141.14g/mol

Ref: 54-PC8204

3-Fluoro-4-methoxyaniline

CAS: 366-99-4

Formula: C₇H₈FNO

Purity: >98.0%(GC)(T)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 141.15

Ref: 3B-F0648

3-Fluoro-4-methoxyaniline

CAS: 366-99-4

3-Fluoro-4-methoxyaniline is a chemical intermediate. It is an aminopyridine that is used in the synthesis of bosutinib, an anticancer drug. 3-Fluoro-4-methoxyaniline binds to the ATP binding site of the cell's mitochondria and prevents the release of cytochrome c from the mitochondria, which leads to apoptosis. 3-Fluoro-4-methoxyaniline also has antimitotic effects and can inhibit the growth of tumor cells. 3-Fluoro-4-methoxyaniline has been shown to have poor cellular uptake, which may be due to its interaction with positron emission tomography (PET) agents such as cyanuric acid or glycopeptide. This chemical has also been shown to be a good surrogate for chloride ions in studies on transfected tumor cells.

Formula: C₇H₈FNO

Purity: Min. 98.5%

Color and Shape: Off-White Powder

Molecular weight: 141.14 g/mol

Ref: 3D-FF64342

3-Fluoro-4-methoxyaniline

CAS: 366-99-4

Formula: C₇H₈FNO

Purity: 96%

Color and Shape: Solid

Molecular weight: 141.145

Ref: 10-F010679