CAS: 366017-09-6 - Mubritinib

Formula: C₂₅H₂₃F₃N₄O₂

InChI: InChI=1S/C25H23F3N4O2/c26-25(27,28)21-9-4-20(5-10-21)8-13-24-30-22(18-34-24)17-33-23-11-6-19(7-12-23)3-1-2-15-32-16-14-29-31-32/h4-14,16,18H,1-3,15,17H2/b13-8+

InChI key: InChIKey=ZTFBIUXIQYRUNT-MDWZMJQESA-N

SMILES: FC(F)(F)C1=CC=C(C=CC2=NC(=CO2)COC3=CC=C(C=C3)CCCCN4N=NC=C4)C=C1

Synonyms:

• 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole
• 1-(4-{4-[(2-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}-1,3-oxazol-4-yl)methoxy]phenyl}butyl)-1H-1,2,3-triazole
• 1H-1,2,3-Triazole, 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-
• Tak 165

Mubritinib

CAS: 366017-09-6

• Formula: C₂₅H₂₃F₃N₄O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 468.4709

Mubritinib

CAS: 366017-09-6

• Formula: C₂₅H₂₃F₃N₄O₂
• Purity: ≥ 95.0%
• Color and Shape: White to off-white powder
• Molecular weight: 468.47

Mubritinib

CAS: 366017-09-6

• Formula: C₂₅H₂₃F₃N₄O₂
• Purity: >98.0%(HPLC)
• Color and Shape: White to Gray to Brown powder to crystal
• Molecular weight: 468.48

Mubritinib

CAS: 366017-09-6

Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.

• Formula: C₂₅H₂₃F₃N₄O₂
• Purity: 98.61% - 99.87%
• Color and Shape: Solid
• Molecular weight: 468.47

Mubritinib

CAS: 366017-09-6

Irreversible inhibitor of HER2 tyrosine kinase

• Formula: C₂₅H₂₃F₃N₄O₂
• Purity: Min. 95%
• Molecular weight: 468.47 g/mol