(S)-Gallopamil hydrochloride is a calcium channel blocker primarily used in the treatment of cardiovascular conditions, particularly for managing hypertension and certain types of arrhythmias. It is a chiral compound, meaning it exists in two enantiomeric forms, with the (S)-enantiomer being the pharmacologically active form. The substance functions by inhibiting the influx of calcium ions through L-type calcium channels, leading to vasodilation and a reduction in heart rate. This compound is typically administered in its hydrochloride salt form, which enhances its solubility and bioavailability. In terms of physical properties, (S)-Gallopamil hydrochloride is usually presented as a white to off-white crystalline powder. It is soluble in water and exhibits stability under standard storage conditions. The compound's pharmacokinetics include moderate absorption and a significant first-pass metabolism, which influences its dosing regimen. As with many medications, potential side effects may include dizziness, headache, and gastrointestinal disturbances, necessitating careful monitoring during treatment.

(S)-Gallopamil hydrochloride

36622-39-6: (S)-Gallopamil hydrochloride is a calcium channel blocker primarily used in the treatment of cardiovascular conditions, particularly for managing hypertension and certain types of arrhythmias. It is a chiral compound, meaning it exists in two enantiomeric forms, with the (S)-enantiomer being the pharmacologically active form. The substance functions by inhibiting the influx of calcium ions through L-type calcium channels, leading to vasodilation and a reduction in heart rate. This compound is typically administered in its hydrochloride salt form, which enhances its solubility and bioavailability. In terms of physical properties, (S)-Gallopamil hydrochloride is usually presented as a white to off-white crystalline powder. It is soluble in water and exhibits stability under standard storage conditions. The compound's pharmacokinetics include moderate absorption and a significant first-pass metabolism, which influences its dosing regimen. As with many medications, potential side effects may include dizziness, headache, and gastrointestinal disturbances, necessitating careful monitoring during treatment.

<p>Gallopamil HCl, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms.</p>

CAS 36622-39-6

(S)-Gallopamil hydrochloride

Gallopamil HCl, (-)-

Ref: TM-T24082