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CAS 366807-79-6

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2-ethynyl-1,3,5-trifluorobenzene

Description:
2-Ethynyl-1,3,5-trifluorobenzene is an aromatic compound characterized by the presence of a trifluoromethyl group and an ethynyl substituent on a benzene ring. The trifluoromethyl groups contribute to the compound's unique electronic properties, enhancing its reactivity and making it a valuable intermediate in organic synthesis. The ethynyl group introduces a triple bond, which can participate in various coupling reactions, such as Sonogashira or alkyne metathesis. This compound is typically a colorless to pale yellow liquid or solid, depending on its state at room temperature. Its molecular structure imparts significant polarity and potential for hydrogen bonding, influencing its solubility in organic solvents. Additionally, the presence of fluorine atoms can enhance thermal stability and alter the compound's physical properties, such as boiling and melting points. Due to its unique characteristics, 2-ethynyl-1,3,5-trifluorobenzene is of interest in materials science and pharmaceuticals, particularly in the development of fluorinated compounds with specific functional properties.
Formula:C8H3F3
InChI:InChI=1/C8H3F3/c1-2-6-7(10)3-5(9)4-8(6)11/h1,3-4H
SMILES:C#Cc1c(cc(cc1F)F)F
Synonyms:
  • 1-Ethynyl-2,4,6-trifluorobenzene
  • Benzene, 2-ethynyl-1,3,5-trifluoro-
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