CAS 36688-78-5

Clindamycin palmitate

Description:

Clindamycin palmitate is an ester derivative of clindamycin, a lincosamide antibiotic, primarily used for its antibacterial properties. It is characterized by its white to off-white crystalline powder form, which is soluble in organic solvents but has limited solubility in water. The substance is typically used in oral formulations, particularly for pediatric patients, due to its palmitate ester form, which enhances its palatability and absorption. Clindamycin palmitate acts by inhibiting bacterial protein synthesis, making it effective against a variety of Gram-positive bacteria and certain anaerobic organisms. It is important to note that, like other antibiotics, clindamycin palmitate may lead to antibiotic resistance if misused. The compound is generally well-tolerated, but it can cause side effects such as gastrointestinal disturbances and, in rare cases, severe colitis. Proper storage conditions are essential to maintain its stability and efficacy, typically requiring protection from light and moisture. As with any medication, it should be used under the guidance of a healthcare professional.

Formula: C₃₄H₆₃ClN₂O₆S

InChI: InChI=1S/C34H63ClN2O6S/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-21-27(38)42-32-30(40)29(39)31(43-34(32)44-5)28(24(3)35)36-33(41)26-22-25(20-7-2)23-37(26)4/h24-26,28-32,34,39-40H,6-23H2,1-5H3,(H,36,41)/t24-,25+,26-,28+,29+,30-,31+,32+,34+/m0/s1

InChI key: InChIKey=OYSKUZDIHNKWLV-PRUAPSLNSA-N

SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)([C@H](C)Cl)[C@]2(O[C@H](SC)[C@H](OC(CCCCCCCCCCCCCCC)=O)[C@@H](O)[C@H]2O)[H]

Synonyms:

• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-hexadecanoate, (2S-trans)-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-hexadecanoate
• Clindamycin 2-palmitate
• Clindamycin palmitate
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-hexadecanoate
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-hexadecanoate, (2S-trans)-

Clindamycin palmitate hydrochloride

CAS: 36688-78-5

Formula: C₃₄H₆₄Cl₂N₂O₆S

Molecular weight: 699.85

Ref: 7W-GA2166

Clindamycin Palmitate

Controlled Product

CAS: 36688-78-5

Formula: C₃₄H₆₃ClN₂O₆S

Color and Shape: Neat

Molecular weight: 663.392

Ref: TR-C580118

Clindamycin palmitate hydrochloride

CAS: 36688-78-5

Clindamycin palmitate hydrochloride is a semisynthetic antibiotic prodrug, which is derived from the lincomycin family, originally sourced from the bacterium *Streptomyces lincolnensis*. This compound functions through its conversion into the active form, clindamycin, once inside the body. Clindamycin acts by inhibiting bacterial protein synthesis, binding to the 50S subunit of the bacterial ribosome, thereby impeding peptide chain initiation and elongation.

Formula: C₃₄H₆₃ClN₂O₆S

Purity: Min. 95%

Molecular weight: 663.4 g/mol

Ref: 3D-LBA68878

Clindamycin Palmitate

CAS: 36688-78-5

Formula: C₃₄H₆₃ClN₂O₆S

Molecular weight: 663.4

Ref: ST-EA-CP-C26109