Description:2,5-Difluoroaniline is an aromatic amine characterized by the presence of two fluorine atoms located at the 2 and 5 positions on the aniline ring. Its molecular formula is C6H5F2N, indicating that it contains six carbon atoms, five hydrogen atoms, two fluorine atoms, and one nitrogen atom. This compound typically appears as a colorless to pale yellow liquid or solid, depending on the temperature. It has a relatively low boiling point and is soluble in organic solvents. 2,5-Difluoroaniline is known for its applications in the synthesis of various pharmaceuticals, agrochemicals, and dyes, owing to its reactivity and the influence of the fluorine substituents on its chemical properties. The presence of fluorine can enhance the compound's stability and lipophilicity, making it valuable in medicinal chemistry. However, like many anilines, it may pose health risks, including potential toxicity, and should be handled with appropriate safety precautions in laboratory settings.
2,5-Difluoroaniline was used in the synthesis of 2,4-di-tert-butyl-6-[(2,5-difluorophenyl)iminomethyl]phenol. It was also used in ultrasound-assisted preparation …
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