CAS 367273-07-2

Benzoic acid, 4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetraMethyl-2-naphthalenyl)carbonyl]aMino]-2,6-difluoro-

CAS: 367273-07-2

Formula: C₂₂H₂₂ClF₂NO₄

Purity: 99.76%

Molecular weight: 437.8642

Ref: IN-DA00C6KT

AGN 195183

CAS: 367273-07-2

AGN 195183 is a cell factor that is a specific agonist for the stem cell factor receptor. It can be used to study transcriptional regulation, such as in the case of hepatitis. AGN 195183 has been shown to be a potent inducer of growth and differentiation in primary cells, as well as being an effective inhibitor of cell proliferation when used at high concentrations. AGN 195183 is also a synthetic retinoid that has been shown to stimulate gene expression by binding to nuclear receptors that regulate transcription-polymerase chain reactions (PCR). This compound can also be used to induce differentiation of cultured cells, such as those derived from Mcf-7 cells.

Formula: C₂₂H₂₂ClF₂NO₄

Purity: Min. 95%

Molecular weight: 437.86 g/mol

Ref: 3D-SPA27307

AGN-195183

CAS: 367273-07-2

AGN 195183: RARα agonist, Kd=3 nM, selective, no RARβ/γ effect, inhibits breast cancer cells, in Phase I/II clinical trials, non-irritant.

Formula: C₂₂H₂₂ClF₂NO₄

Color and Shape: Solid

Molecular weight: 437.86

Ref: TM-T14144