CAS 367514-88-3

Lurasidone hydrochloride

Description:

Lurasidone hydrochloride is an atypical antipsychotic medication primarily used in the treatment of schizophrenia and bipolar disorder. It functions as a dopamine D2 receptor antagonist and a serotonin 5-HT2A receptor antagonist, which helps to balance neurotransmitters in the brain, thereby alleviating symptoms associated with these mental health conditions. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration in tablet form. Its chemical formula reflects a complex structure that includes multiple functional groups, contributing to its pharmacological activity. Lurasidone hydrochloride is known for its relatively favorable side effect profile compared to other antipsychotics, with a lower incidence of weight gain and metabolic syndrome. However, like all medications, it may still cause side effects, including sedation and extrapyramidal symptoms. It is essential for patients to be monitored regularly by healthcare professionals during treatment to ensure efficacy and safety.

Formula: C₂₈H₃₆N₄O₂S·ClH

InChI: InChI=1S/C28H36N4O2S.ClH/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26;/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2;1H/t18-,19+,20-,21-,24+,25-;/m0./s1

InChI key: InChIKey=NEKCRUIRPWNMLK-SCIYSFAVSA-N

SMILES: O=C1[C@]2([C@]([C@]3(C[C@@]2(CC3)[H])[H])(C(=O)N1C[C@H]4[C@H](CN5CCN(CC5)C=6C=7C(SN6)=CC=CC7)CCCC4)[H])[H].Cl

Synonyms:

• 4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, (3aR,4S,7R,7aS)- hydrochloride
• 4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, hydrochloride (1:1), (3aR,4S,7R,7aS)-
• 4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, monohydrochloride, (3aR,4S,7R,7aS)-
• Latuda
• Lurasidone HCl
• Lurasidone Hydrochloride
• Sm 13496

Lurasidone Hydrochloride

CAS: 367514-88-3

Compounds containing a benzothiazole ring-system (whether or not hydrogenated), not further fused

Formula: C₂₈H₃₆N₄O₂S·HCl

Color and Shape: White Off-White Powder

Molecular weight: 528.23258

Ref: 45-1370815

Lurasidone hydrochloride

CAS: 367514-88-3

Lurasidone hydrochloride

Purity: ≥98%

Molecular weight: 529.14g/mol

Ref: 54-BUP13175

Lurasidone Hydrochloride

CAS: 367514-88-3

Lurasidone Hydrochloride

Purity: 99%

Molecular weight: 529.14g/mol

Ref: 54-OR1025562

Lurasidone HCl

CAS: 367514-88-3

Formula: C₂₈H₃₆N₄O₂S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 492.68 36.46

Ref: 4Z-L-090001

Lurasidone Hydrochloride

Controlled Product

CAS: 367514-88-3

Formula: C₂₈H₃₆N₄O₂S·ClH

Color and Shape: Neat

Molecular weight: 529.14

Ref: 86-MM3647.00

Lurasidone hydrochloride

CAS: 367514-88-3

Lurasidone HCl: Atypical antipsychotic, treats schizophrenia & bipolar, affects dopamine, serotonin & adrenergic receptors.

Formula: C₂₈H₃₆N₄O₂S·HCl

Purity: 99.51%

Color and Shape: Solid

Molecular weight: 529.14

Ref: TM-T1735

Lurasidone Hydrochloride

CAS: 367514-88-3

Applications An antipsychotic used for treatment of schizophrenia.
References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007), Cole, P., et al.: Drugs of the Fut., 33, 316 (2008),

Formula: C₂₈H₃₆N₄O₂S·ClH

Color and Shape: White

Molecular weight: 529.14

Ref: TR-L474920

Lurasidone-d8 Hydrochloride

Controlled Product

CAS: 1132654-54-6, 367514-88-3

Applications A labelled analog of the antipsychotic Lurasidone, used for treatment of schizophrenia.
References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007), Cole, P., et al.: Drugs of the Fut., 33, 316 (2008),

Formula: C₂₈H₂₈D₈N₄O₂S·HCl

Color and Shape: Neat

Molecular weight: 537.00

Ref: TR-L474922

Lurasidone hydrochloride

Controlled Product

CAS: 367514-88-3

Lurasidone hydrochloride is an atypical antipsychotic medication, which is a synthetic pharmaceutical compound. It is derived from a chemical synthesis process, utilizing a specific arrangement of atoms to create an effective therapeutic agent. The mode of action for lurasidone hydrochloride involves antagonism of dopamine D2 and serotonin 5-HT2A receptors. This interaction is crucial in modulating neurotransmitter activity, which is often dysregulated in certain psychiatric conditions.The primary uses and applications of lurasidone hydrochloride are in the management of schizophrenia and bipolar depression. By targeting the key receptors associated with these disorders, lurasidone helps to stabilize mood, reduce psychotic symptoms, and improve overall cognitive function. Its receptor affinity profile allows for a lower incidence of some side effects commonly associated with other antipsychotics, like metabolic syndrome and weight gain. Researchers and clinicians find lurasidone hydrochloride valuable due to its efficacy and favorable side effect profile, which contributes to its widespread use in clinical psychiatric settings.

Formula: C₂₈H₃₇ClN₄O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 529.14 g/mol

Ref: 3D-FL24958

Trans Lurasidone Hydrochloride

Controlled Product

CAS: 367514-88-3

Formula: C₂₈H₃₆N₄O₂S·HCl

Color and Shape: Neat

Molecular weight: 529.14

Ref: TR-L474960