CAS 36798-79-5

Budralazine

Description:

Budralazine is a chemical compound classified as a hydrazine derivative, primarily known for its use as an antihypertensive agent. It functions by acting as a vasodilator, helping to lower blood pressure by relaxing blood vessels. The molecular structure of Budralazine includes a hydrazine moiety, which contributes to its pharmacological activity. It is typically administered in the form of its hydrochloride salt to enhance solubility and bioavailability. Budralazine exhibits moderate lipophilicity, allowing it to penetrate biological membranes effectively. Its mechanism of action involves the inhibition of vascular smooth muscle contraction, leading to vasodilation. While it has therapeutic applications, potential side effects may include dizziness, headache, and gastrointestinal disturbances. As with many medications, careful monitoring is essential to manage any adverse reactions and ensure efficacy. Budralazine's safety profile and pharmacokinetics are important considerations in clinical settings, particularly for patients with cardiovascular conditions. Overall, Budralazine represents a significant compound in the realm of antihypertensive therapies.

Formula: C₁₄H₁₆N₄

InChI: InChI=1S/C14H16N4/c1-10(2)8-11(3)16-18-14-13-7-5-4-6-12(13)9-15-17-14/h4-9H,1-3H3,(H,17,18)

InChI key: InChIKey=DQGFCLJXYFXXIJ-UHFFFAOYSA-N

SMILES: N(N=C(C=C(C)C)C)C=1C2=C(C=NN1)C=CC=C2

Synonyms:

• 1(2H)-Phthalazinone, (1,3-dimethyl-2-butenylidene)hydrazone
• 1-(2-(1,3-Dimethyl-2-Butenylidene)Hydrazino)Phthalazine
• 1-[(2E)-2-(1,3-dimethylbut-2-en-1-ylidene)hydrazino]phthalazine
• 1-[2-(1,3-Dimethyl-2-buten-1-ylidene)hydrazino]phthalazine
• 1-[2-(4-Methylpent-3-En-2-Ylidene)Hydrazinyl]Phthalazine
• 3-Penten-2-one, 4-methyl-, 2-(1-phthalazinyl)hydrazone
• Buterazine
• Dj 1461
• Budralazine

SB 206553 hydrochloride

CAS: 36798-79-5

SB 206553 hydrochloride

Purity: ≥98%

Molecular weight: 328.8g/mol

Ref: 54-BUP20585

Budralazine

Controlled Product

CAS: 36798-79-5

Applications Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.
References Moroi, R. et al.: Chem. Pharmac. Bull., 24, 2850 (1976); Ono, K. et al.: Xenobiotica, 9, 227 (1979); Yoshioka, M. et al.: Prog. Hypertens., 1992, 309 (1992);

Formula: C₁₄H₁₆N₄

Color and Shape: Neat

Molecular weight: 240.3

Ref: TR-B689515

Budralazine

CAS: 36798-79-5

Budralazine is an agent of antihypertensive drug.

Formula: C₁₄H₁₆N₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 240.3

Ref: TM-T23834

Budralazine

CAS: 36798-79-5

Budralazine is a synthetic vasodilator, which is derived from a series of hydrazine analogs, known for their ability to modulate vascular tone. Its mode of action involves the direct relaxation of vascular smooth muscle. This relaxation leads to a decrease in peripheral vascular resistance and, consequently, a reduction in blood pressure. Intriguingly, Budralazine is thought to selectively target arterioles over veins, making it of particular interest in the study of vascular dynamics and hypertension.

Formula: C₁₄H₁₆N₄

Purity: Min. 95%

Molecular weight: 240.3 g/mol

Ref: 3D-LBA79879