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CAS 36889-17-5

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Gentamicin X2

Description:
Gentamicin X2, identified by the CAS number 36889-17-5, is an aminoglycoside antibiotic derived from the bacterium Micromonospora purpurea. It exhibits broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, making it effective in treating various infections. The substance is characterized by its ability to inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit, which disrupts the translation process. Gentamicin X2 is typically administered via injection and is known for its relatively low toxicity compared to other aminoglycosides, although it can still cause nephrotoxicity and ototoxicity with prolonged use or high doses. Its pharmacokinetics involve rapid distribution in body tissues, with renal excretion being the primary route of elimination. Gentamicin X2 is often used in combination with other antibiotics to enhance its efficacy and reduce the risk of resistance development. As with all antibiotics, appropriate susceptibility testing is recommended to ensure its effectiveness against specific bacterial strains.
Formula:C19H38N4O10
InChI:InChI=1S/C19H38N4O10/c1-19(29)5-30-18(13(28)16(19)23-2)33-15-7(21)3-6(20)14(12(15)27)32-17-9(22)11(26)10(25)8(4-24)31-17/h6-18,23-29H,3-5,20-22H2,1-2H3/t6-,7+,8+,9+,10+,11+,12-,13+,14+,15-,16+,17+,18+,19-/m0/s1
InChI key:InChIKey=HFLKNINDVFJPQT-ZFAMMYHGSA-N
SMILES:O([C@H]1[C@H](O)[C@@H](O[C@@H]2[C@H](O)[C@@H](NC)[C@@](C)(O)CO2)[C@H](N)C[C@@H]1N)[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N
Synonyms:
  • 36889-17-5
  • <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-
  • Gentamicin X
  • Gentamicin X2
  • Gentamicin X<sub>2</sub>
  • Gentamycin X
  • Gentamycin X2
  • O-2-Amino-2-deoxy-a-D-glucopyranosyl-(1?4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(1?6))-2-deoxy-D-streptamine
  • O-2-Amino-2-deoxy-α-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</smallcap>-arabinopyranosyl-(1→6)]-2-deoxy-<smallcap>D</span>-streptamine
  • D-Streptamine, O-2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-
  • (1R,2S,3S,4R,6S)-4,6-Diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
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