CAS 368890-20-4

2-[[(4-Chloro-3-methoxy-2-pyridinyl)methyl]thio]-6-(difluoromethoxy)-1H-benzimidazole

Description:

2-[[(4-Chloro-3-methoxy-2-pyridinyl)methyl]thio]-6-(difluoromethoxy)-1H-benzimidazole is a chemical compound characterized by its complex structure, which includes a benzimidazole core substituted with various functional groups. The presence of a thioether linkage, specifically the methylthio group attached to a pyridine ring, contributes to its unique reactivity and potential biological activity. The difluoromethoxy group enhances its lipophilicity and may influence its pharmacokinetic properties. This compound is often studied for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. Its chlorinated and methoxy-substituted pyridine moiety may also play a role in modulating interactions with biological targets. Overall, the combination of these functional groups suggests that this compound could exhibit interesting properties, making it a candidate for further research in drug discovery and development.

Formula: C₁₅H₁₂ClF₂N₃O₂S

InChI: InChI=1S/C15H12ClF2N3O2S/c1-22-13-9(16)4-5-19-12(13)7-24-15-20-10-3-2-8(23-14(17)18)6-11(10)21-15/h2-6,14H,7H2,1H3,(H,20,21)

InChI key: InChIKey=SEHIARBDRGKABK-UHFFFAOYSA-N

SMILES: S(CC1=C(OC)C(Cl)=CC=N1)C=2NC=3C(N2)=CC=C(OC(F)F)C3

Synonyms:

• 1H-Benzimidazole, 2-[[(4-chloro-3-methoxy-2-pyridinyl)methyl]thio]-5-(difluoromethoxy)-
• 1H-Benzimidazole, 2-[[(4-chloro-3-methoxy-2-pyridinyl)methyl]thio]-6-(difluoromethoxy)-
• 2-(((4-Chloro-3-methoxypyridin-2-yl)methyl)thio)-5-(difluoromethoxy)-1H-benzo[d]imidazole
• 2-[(4-Chloro-3-methoxypyridin-2-yl)methylsulfanyl]-6-(difluoromethoxy)-1H-benzimidazole
• 2-[[(4-Chloro-3-methoxy-2-pyridinyl)methyl]thio]-6-(difluoromethoxy)-1H-benzimidazole
• 2-[[(4-Chloro-3-methoxy-2-pyridyl)methyl]thio]-5-(difluoromethoxy)-1H-benzimidazole
• 2-{[(4-chloro-3-methoxypyridin-2-yl)methyl]sulfanyl}-6-(difluoromethoxy)-1H-benzimidazole
• 5-(Difluoromethoxy)-2-[[(3-methoxy-4-chloro-2-pyridinyl)methyl]mercapto]-1H-benzimidazole
• 5-Difluoromethoxy-2-[(4-Chloro-3-methoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
• 5-(Difluoromethoxy)-2[[(4-chloro-3-methoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole

2-(((4-Chloro-3-methoxypyridin-2-yl)methyl)thio)-5-(difluoromethoxy)-1H-benzo[d]imidazole

CAS: 368890-20-4

Formula: C₁₅H₁₂ClF₂N₃O₂S

Purity: 98%

Molecular weight: 371.7895

Ref: IN-DA0077NM

5-Difluoromethoxy-2-[(4-Chloro-3-Methoxy-2-Pyridinyl)Methyl]Thio-1H-Benzimidazole

CAS: 368890-20-4

5-Difluoromethoxy-2-[(4-Chloro-3-Methoxy-2-Pyridinyl)Methyl]Thio-1H-Benzimidazole

Purity: 98%

Molecular weight: 371.79g/mol

Ref: 54-PC105283

Pantoprazole Impurity 43

CAS: 368890-20-4

Formula: C₁₅H₁₂ClF₂N₃O₂S

Color and Shape: White To Off-White Solid

Molecular weight: 371.79

Ref: 4Z-P-0164

5-(Difluoromethoxy)-2[[(4-chloro-3-methoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole

Controlled Product

CAS: 368890-20-4

Applications 5-(Difluoromethoxy)-2[[(4-chloro-3-methoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole is used in the preparation of isotopically substituted pantoprazole for treating gastrointestinal disorders.
References Kohl, B., et al.: PCT. Int. Appl., (2007) WO 2007012651 A1;

Formula: C₁₅H₁₂ClF₂N₃O₂S

Color and Shape: Neat

Molecular weight: 371.789

Ref: TR-D368890

Pantoprazole Impurity 43

CAS: 368890-20-4

Formula: C₁₅H₁₂ClF₂N₃O₂S

Molecular weight: 371.79

Ref: ST-EA-CP-P15060