CAS 368891-70-7

N-[4-[(5S)-5-[(Acetylamino)methyl]-2-oxo-3-oxazolidinyl]-2-fluorophenyl]-N-(2-hydroxyethyl)glycine

Description:

N-[4-[(5S)-5-[(Acetylamino)methyl]-2-oxo-3-oxazolidinyl]-2-fluorophenyl]-N-(2-hydroxyethyl)glycine, with CAS number 368891-70-7, is a synthetic compound characterized by its complex structure, which includes an oxazolidinone ring, a fluorophenyl group, and a glycine derivative. This compound features multiple functional groups, including an acetylamino group and a hydroxyethyl substituent, contributing to its potential biological activity. The presence of the fluorine atom may enhance its pharmacological properties, such as increased lipophilicity or altered metabolic stability. The stereochemistry indicated by the (5S) designation suggests that the compound may exhibit specific interactions with biological targets, potentially influencing its efficacy and safety profile. Such compounds are often investigated for their roles in medicinal chemistry, particularly in the development of antibiotics or other therapeutic agents. Overall, the unique combination of structural elements in this compound may confer interesting properties that warrant further research in pharmaceutical applications.

Formula: C₁₆H₂₀FN₃O₆

InChI: InChI=1S/C16H20FN3O6/c1-10(22)18-7-12-8-20(16(25)26-12)11-2-3-14(13(17)6-11)19(4-5-21)9-15(23)24/h2-3,6,12,21H,4-5,7-9H2,1H3,(H,18,22)(H,23,24)/t12-/m0/s1

InChI key: InChIKey=JGOXQNABWWZJSO-LBPRGKRZSA-N

SMILES: O=C1N(C2=CC(F)=C(N(CC(O)=O)CCO)C=C2)C[C@H](CNC(C)=O)O1

Synonyms:

• PNU 142586
• N-[4-[(5S)-5-[(Acetylamino)methyl]-2-oxo-3-oxazolidinyl]-2-fluorophenyl]-N-(2-hydroxyethyl)glycine
• Glycine, N-[4-[(5S)-5-[(acetylamino)methyl]-2-oxo-3-oxazolidinyl]-2-fluorophenyl]-N-(2-hydroxyethyl)-

PNU-142586

CAS: 368891-70-7

PNU-142586 is a bio-active chemical.

Formula: C₁₆H₂₀FN₃O₆

Color and Shape: Solid

Molecular weight: 369.34

Ref: TM-T34097

Linezolid Impurity 14 (PNU142586)

CAS: 368891-70-7

Formula: C₁₆H₂₀FN₃O₆

Molecular weight: 369.35

Ref: 4Z-L-0732

PNU 142586 Sodium Salt

CAS: 368891-70-7

Applications PNU 142586 Sodium Salt is an inactive metabolite of Linezolid (L466500).
References Shinabarger, D., et al.: Antimicrob. Agents Chemother., 41, 2132 (1997), Wynalda, M., et al.: Drug Metab. Dispos., 28, 1014 (2000),

Formula: C₁₆H₁₉FN₃NaO₆

Color and Shape: White To Off-White

Molecular weight: 391.33

Ref: TR-P653405

PNU 142586-13C-d2 Sodium Salt

Controlled Product

CAS: 368891-70-7

Formula: CC₁₅D₂H₁₇FN₃O₆·Na

Color and Shape: Neat

Molecular weight: 394.332

Ref: TR-P653407

PNU 142586

CAS: 368891-70-7

PNU 142586 is a drug that inhibits protein synthesis by binding to the 50S ribosomal subunit. It has been shown to be effective against infectious diseases, including tuberculosis and HIV. PNU 142586 also reduces the incidence of drug reactions in patients with hepatic impairment. The concentration-time curve for PNU 142586 shows that it is rapidly absorbed and eliminated from the body, which may be due to its rapid metabolism by esterases. Animal studies have shown that PNU 142586 is not toxic to humans, but it has been shown to cause liver damage in rats. Clinical studies have found that PNU 142586 is effective at treating tuberculosis in humans, although more research into adverse effects on other organs is needed. Urea nitrogen levels were found to increase during treatment with PNU 142586, which may be due to its effect on protein synthesis.br>

Formula: C₁₆H₂₀FN₃O₆

Purity: Min. 95%

Molecular weight: 369.35 g/mol

Ref: 3D-FP175532

Linezolid Impurity 14

CAS: 368891-70-7

Formula: C₁₆H₂₀FN₃O₆

Molecular weight: 369.35

Ref: ST-EA-CP-L40028