CAS 36894-69-6: Labetalol

Description: Labetalol is a medication primarily used to treat high blood pressure and hypertension. It is classified as a non-selective beta-blocker with alpha-1 blocking activity, which helps to lower blood pressure by reducing heart rate and relaxing blood vessels. The chemical formula of labetalol is C19H24N2O3, and it features a complex structure that includes a phenolic hydroxyl group, an ether linkage, and a secondary amine. Labetalol is known for its unique dual action, which allows it to effectively manage hypertension while minimizing some of the side effects commonly associated with traditional beta-blockers. It is typically administered orally or intravenously, depending on the clinical situation. Common side effects may include dizziness, fatigue, and gastrointestinal disturbances. Due to its pharmacological profile, labetalol is often preferred in certain populations, such as pregnant women, for managing hypertension. Its safety and efficacy have been well-documented in clinical studies, making it a valuable option in the treatment of cardiovascular conditions.

Formula: C₁₉H₂₄N₂O₃

InChI: InChI=1S/C19H24N2O3/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24)

InChI key: InChIKey=SGUAFYQXFOLMHL-UHFFFAOYSA-N

SMILES: O=C(N)C1=CC(=CC=C1O)C(O)CNC(C)CCC=2C=CC=CC2

Synonyms:

• 2-Hydroxy-5-(1-hydroxy-2-((4-phenylbutan-2-yl)amino)ethyl)benzamide
• 2-Hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide
• 2-Hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzamide
• Ah 5158
• Albetol
• Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-
• Ibidomide
• Labetalol

Labetalol

CAS: 36894-69-6

Labetalol: mixed alpha/beta blocker for hypertension, oral or IV; affected by CYP2C19 genetics.

• Formula: C₁₉H₂₄N₂O₃
• Purity: 99.87% - 99.89%
• Color and Shape: Solid
• Molecular weight: 328.41

Labetalol-d6

CAS: 36894-69-6

• Formula: C₁₉H₁₈N₂O₃D₆
• Molecular weight: 334.45

3-Bromo Labetalol

CAS: 36894-69-6

• Formula: C₁₉H₂₃BrN₂O₃
• Color and Shape: Neat
• Molecular weight: 407.30

Labetalol-d3 Hydrochloride (Mixture of Diastereomers)

CAS: 32780-64-6 36894-69-6

• Formula: C₁₉D₃H₂₁N₂O₃·HCl
• Color and Shape: Neat
• Molecular weight: 367.885

2-Hydroxy-5-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl}benzamide

CAS: 36894-69-6

2-Hydroxy-5-[1-hydroxy-2-(3-phenylpropyl)amino]ethylbenzamide (HET0016) is an anti-proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody that binds to the …

• Purity: Min. 95%