CAS 369-34-6

3,4-Difluoronitrobenzene

Description:

3,4-Difluoronitrobenzene is an aromatic compound characterized by the presence of two fluorine atoms and one nitro group attached to a benzene ring. Its molecular formula is C6H4F2N2O2, indicating that it contains six carbon atoms, four hydrogen atoms, two fluorine atoms, two nitrogen atoms, and two oxygen atoms. The compound is typically a pale yellow liquid or solid at room temperature, exhibiting a distinct aromatic odor. It is known for its moderate solubility in organic solvents and limited solubility in water. 3,4-Difluoronitrobenzene is used in various applications, including as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The presence of fluorine atoms enhances its chemical stability and reactivity, making it a valuable building block in organic synthesis. Additionally, it is important to handle this compound with care due to its potential toxicity and environmental impact, necessitating appropriate safety measures during use and disposal.

Formula: C₆H₃F₂NO₂

InChI: InChI=1S/C6H3F2NO2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H

InChI key: InChIKey=RUBQQRMAWLSCCJ-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=CC(F)=C(F)C=C1

Synonyms:

• 1,2-Difluoro-4-Nitrobenzene
• 3,4-Difluornitrobenzene
• 3,4-Difluoro Nitro Benzene
• 3,4-Difluoro nitrobenzene
• 3,4-Difluoro-1-nitrobenzene
• 4-Nitro-1,2-difluorobenzene
• Benzene, 1,2-difluoro-4-nitro-
• 3,4-Difluoronitrobenzene

3,4-Difluoronitrobenzene

CAS: 369-34-6

Formula: C₆H₃F₂NO₂

Purity: >98.0%(GC)

Color and Shape: Light yellow to Brown clear liquid

Molecular weight: 159.09

Ref: 3B-D1926

3,4-Difluoronitrobenzene

CAS: 369-34-6

Formula: C₆H₃F₂NO₂

Purity: 99.0%

Color and Shape: Liquid, Clear

Molecular weight: 159.092

Ref: 10-F001664

1,2-Difluoro-4-nitrobenzene, 98+%

CAS: 369-34-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₃F₂NO₂

Purity: 98+%

Color and Shape: Clear yellow, Liquid

Molecular weight: 159.09

Ref: 02-A11060

3,4-Difluoronitrobenzene

CAS: 369-34-6

Formula: C₆H₃F₂NO₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 159.0903

Ref: IN-DA003IH4

3,4-Difluoronitrobenzene

CAS: 369-34-6

Formula: C₆H₃F₂NO₂

Color and Shape: Pale Yellow Oil

Molecular weight: 159.09

Ref: 4Z-B-139079

3,4-Difluoronitrobenzene, min. 98%

CAS: 369-34-6

Formula: C₆H₃F₂NO₂

Purity: min. 98%

Color and Shape: Yellow liquid

Molecular weight: 159.09

Ref: 08-09-0059

3,4-Difluoronitrobenzene

CAS: 369-34-6

Formula: C₆H₃F₂NO₂

Molecular weight: 159.09

Ref: 7W-GK5937

3,4-Difluoronitrobenzene

CAS: 369-34-6

3,4-Difluoronitrobenzene

Formula: C₆H₃F₂NO₂

Purity: 98%

Color and Shape: clear. faint yellow liquid

Molecular weight: 159.09g/mol

Ref: 54-PC2862

3,4-Difluoronitrobenzene

CAS: 369-34-6

3,4-Difluoronitrobenzene is an antimicrobial agent that inhibits the growth of bacteria. It is synthesized by reacting 3,4-difluorobenzene with nitric acid in a one-step chemical reaction. The optimal reaction conditions are at pH 4 and room temperature. 3,4-Difluoronitrobenzene has low energy and is nucleophilic because it contains a lone pair of electrons on the fluorine atom. It is an acidic compound that can be synthesized using hydrogen chloride and piperazine as starting materials.

Formula: C₆H₃F₂NO₂

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 159.09 g/mol

Ref: 3D-FD64616

3,4-Difluoro-1-nitrobenzene

Controlled Product

CAS: 369-34-6

Applications 3,4-Difluoro-1-nitrobenzene was used in the synthesis of nitrogen-carbon-linked (azolylphenyl)oxazolidinones with antibacterial activities. It was also used in the preparation of (homo)piperazinylphenyl- and piperidinylphenyl-substituted oxazolidinones with antibacterial activities.
References Genin, M., et al.: J. Med. Chem., 43, 953 (2000); Das, B., et al.: Bioorg. Med. Chem. Lett., 15, 4261 (2005)

Formula: C₆H₃F₂NO₂

Color and Shape: Neat

Molecular weight: 159.09

Ref: TR-D445585