CAS 36930-63-9

IAEDANS

Description:

IAEDANS, or 5-Iodoacetamido fluorescein, is a fluorescent dye commonly used in biochemical and cellular imaging applications. It is characterized by its ability to emit fluorescence upon excitation, making it valuable for labeling proteins and other biomolecules. The compound features a fluorescein backbone, which contributes to its strong fluorescent properties, and an iodoacetamido group that allows for covalent attachment to thiol-containing molecules, such as cysteine residues in proteins. IAEDANS is typically used in studies involving protein folding, dynamics, and interactions due to its sensitivity and specificity. Its fluorescence can be modulated by environmental factors, such as pH and polarity, which can provide insights into the local microenvironment of the labeled biomolecules. Additionally, IAEDANS is often utilized in live-cell imaging, allowing researchers to track cellular processes in real time. Overall, its unique chemical structure and fluorescent characteristics make IAEDANS a versatile tool in molecular biology and biochemistry research.

Formula: C₁₄H₁₅IN₂O₄S

InChI: InChI=1S/C14H15IN2O4S/c15-9-14(18)17-8-7-16-12-5-1-4-11-10(12)3-2-6-13(11)22(19,20)21/h1-6,16H,7-9H2,(H,17,18)(H,19,20,21)

InChI key: InChIKey=ZMERMCRYYFRELX-UHFFFAOYSA-N

SMILES: N(CCNC(CI)=O)C=1C2=C(C(S(=O)(=O)O)=CC=C2)C=CC1

Synonyms:

• 1,5-I-Aedans
• 1,5-Iaedans
• 1-Naphthalenesulfonic acid, 5-[(2-aminoethyl)(iodoacetyl)amino]-
• 1-Naphthalenesulfonic acid, 5-[[2-[(2-iodoacetyl)amino]ethyl]amino]-
• 1-Naphthalenesulfonic acid, 5-[[2-[(iodoacetyl)amino]ethyl]amino]-
• 5-(Iodoacetamidoethyl)aminonaphthalene-1-sulfonic acid
• 5-({2-[(Iodoacetyl)Amino]Ethyl}Amino)Naphthalene-1-Sulfonic Acid
• 5-[[2-[(2-Iodoacetyl)amino]ethyl]amino]-1-naphthalenesulfonic acid
• Iaedans
• Iedans
• N-(Iodoacetamidoethyl)-1-aminonaphthalene-5-sulfonic acid
• N-(Iodoacetamidoethyl)-5-naphthylamine-1-sulfonic acid
• N-(Iodoacetyl)-N′-(1-sulfo-5-naphthyl)ethylenediamine
• N-(Iodoacetylaminoethyl)-5-naphthylamine-1-sulfonic acid
• N-Iodoacetyl-N-(5-sulfo-1-naphthyl)ethylenediamine
• N-[2-(Iodoacetylamino)ethyl]-5-naphthylamine-1-sulfonic acid

1,5-I-AEDANS

CAS: 36930-63-9

Formula: C₁₄H₁₅IN₂O₄S

Purity: 93%

Color and Shape: Solid

Molecular weight: 434.2494

Ref: IN-DA00BXX9

N-(Iodoacetaminoethyl)-1-naphthylamine-5-sulphonic acid

CAS: 36930-63-9

N-(Iodoacetaminoethyl)-1-naphthylamine-5-sulphonic acid

Formula: C₁₄H₁₅IN₂O₄S

Purity: By hplc: 97.4% (Typical Value in Batch COA)

Color and Shape: off-white powder

Molecular weight: 434.25g/mol

Ref: 54-BII7028

N-(Iodoacetylaminoethyl)-5-Naphthylamine-1-Sulfonic Acid

Controlled Product

CAS: 36930-63-9

Stability Hygroscopic, Light Sensitive, Moisture Sensitive
Applications A fluorescent sulfhydryl reagent which is sensitive to photo catalyzed degradation in both aqueous solution and organic solvents. It readily reacts with both thiol compounds and sulfhydryl groups to provide photo stable covalent derivatives.Fluorescence: max. Abs. l = 336nm, max. Em. l = 490 nm.
References Hudson, E.N. and Weber, G.: Biochem, 12(21), 4154-4161 (1973)

Formula: C₁₄H₁₅IN₂O₄S

Purity: ~90%

Color and Shape: Neat

Molecular weight: 434.25

Ref: TR-I685600

N-(Iodoacetylaminoethyl)-5-naphthylamine-1-sulfonic acid

CAS: 36930-63-9

A naphthylamine sulfonic acid with activated linker.  Soluble in DMSO (ca 4mg/ml)

Formula: C₁₄H₁₅IN₂O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 434.25 g/mol

Ref: 3D-FI24611