CAS 36948-76-2

Oroxylin A 7-O-glucuronide

Description:

Oroxylin A 7-O-glucuronide is a flavonoid compound derived from Oroxylum indicum, a plant known for its medicinal properties. This compound is a glycoside, meaning it consists of a flavonoid moiety (oroxylin A) linked to a glucuronic acid unit. It exhibits various biological activities, including antioxidant, anti-inflammatory, and potential anticancer properties, making it of interest in pharmacological research. Oroxylin A 7-O-glucuronide is soluble in polar solvents due to its glucuronide group, which enhances its bioavailability. The compound's structure contributes to its ability to interact with various biological targets, influencing cellular signaling pathways. Additionally, it may play a role in the detoxification processes in the liver, as glucuronidation is a common metabolic pathway for many xenobiotics. Research continues to explore its therapeutic potential and mechanisms of action, particularly in the context of traditional medicine and modern pharmacology. Overall, Oroxylin A 7-O-glucuronide represents a significant area of interest in natural product chemistry and drug development.

Formula: C₂₂H₂₀O₁₁

InChI: InChI=1S/C22H20O11/c1-30-19-13(32-22-18(27)16(25)17(26)20(33-22)21(28)29)8-12-14(15(19)24)10(23)7-11(31-12)9-5-3-2-4-6-9/h2-8,16-18,20,22,24-27H,1H3,(H,28,29)/t16-,17-,18+,20-,22+/m0/s1

InChI key: InChIKey=QXIPXNZUEQYPLZ-QSUZLTIMSA-N

SMILES: OC1=C2C(=CC(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)=C1OC)OC(=CC2=O)C4=CC=CC=C4

Synonyms:

• Oroxylin A 7-O-glucuronide
• Oroxylin 7-glucuronide
• β-D-Glucopyranosiduronic acid, 5-hydroxy-6-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
• 5-Hydroxy-6-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid
• 6-Methoxybaicalein 7-glucuronide
• Oroxyloside
• Oroxylin A-7-O-β-D-glucuronide
• Oroxylin A-7-O-beta-D-glucuronide
• Oroxylin A 7-glucuronide
• 5-Hydroxy-6-methoxy-7-(β-D-glucurono pyranosyloxy)flavone
• 5-Hydroxy-6-methoxy-2-phenyl-4-oxo-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid
• OROXYLOSIDE; OROXYLIN A 7-GLUCURONIDE

Oroxylin A-7-O-glucuronide

CAS: 36948-76-2

Formula: C₂₂H₂₀O₁₁

Purity: 98%

Molecular weight: 460.3876

Ref: IN-DA00C7TY

Oroxylin A-7-O-glucuronide

CAS: 36948-76-2

Oroxylin A-7-O-glucuronide

Purity: ≥98%

Molecular weight: 460.39g/mol

Ref: 54-BUP02924

Oroxyloside

CAS: 36948-76-2

Formula: C₂₂H₂₀O₁₁

Molecular weight: 460.39

Ref: 7W-GY9571

Oroxyloside

CAS: 36948-76-2

Formula: C₂₂H₂₀O₁₁

Purity: 95%~99%

Molecular weight: 460.391

Ref: BP-BP1046

Oroxylin A 7-O-β-d-glucuronide

CAS: 36948-76-2

Oroxylin A 7-O-β-d-glucuronide is a flavonoid glucuronide extracted with prolyl oligopeptidase (POP) inhibitory properties.

Formula: C₂₂H₂₀O₁₁

Purity: 99.32% - 99.67%

Color and Shape: Solid

Molecular weight: 460.39

Ref: TM-T3891

Oroxylin a 7-glucuronide

CAS: 36948-76-2

Natural glycoside

Formula: C₂₂H₂₀O₁₁

Purity: ≥ 90.0 % (HPLC)

Molecular weight: 460.39

Ref: 5G-84247

Oroxylin A 7-O-glucuronide

CAS: 36948-76-2

Oroxylin A 7-O-glucuronide (OA7G) is a natural compound that exhibits anti-angiogenic and anti-inflammatory effects. OA7G binds to p-hydroxybenzoic acid and inhibits the activity of glycosidases, which are enzymes that hydrolyze glycosides. OA7G has been shown to have therapeutic potential in several models of inflammatory bowel disease. In vivo studies show that OA7G may be a useful agent for the treatment of bowel disease by inhibiting angiogenesis, which is the formation of new blood vessels from pre-existing ones. Molecular docking analysis showed binding affinity between OA7G and the enzyme dextran sulfate glucuronyltransferase, suggesting a possible mechanism for its anti-inflammatory effects.

Formula: C₂₂H₂₀O₁₁

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 460.39 g/mol

Ref: 3D-MO74545