CAS 3695-80-5

H-Ala-D-Ala-OH

Description:

H-Ala-D-Ala-OH, also known as L-Alanine-D-Alanine, is a dipeptide that consists of two amino acids: L-alanine and D-alanine. This compound is notable for its role in the biosynthesis of peptidoglycan, a critical component of bacterial cell walls. The presence of both L- and D-forms of alanine is significant, as it contributes to the structural integrity and resistance of bacterial cell walls to enzymatic degradation. H-Ala-D-Ala-OH is typically a white to off-white crystalline solid, soluble in water, and exhibits a neutral pH in solution. Its molecular structure includes an amine group, a carboxylic acid group, and a side chain characteristic of alanine, which influences its biochemical interactions. This dipeptide is of interest in pharmaceutical research, particularly in the development of antibiotics that target bacterial cell wall synthesis. Additionally, it serves as a model compound in studies of peptide synthesis and protein structure.

Formula: C₆H₁₂N₂O₃

InChI: InChI=1/C6H12N2O3/c1-3(7)5(9)8-4(2)6(10)11/h3-4H,7H2,1-2H3,(H,8,9)(H,10,11)/t3?,4-/m1/s1

SMILES: CC(C(=N[C@H](C)C(=O)O)O)N

H-Ala-D-Ala-OH

CAS: 3695-80-5

Bachem ID: 4002261.

Formula: C₆H₁₂N₂O₃

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 160.17

Ref: 01-4002261

D-Alanine, L-alanyl-

CAS: 3695-80-5

Formula: C₆H₁₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 160.1711

Ref: IN-DA0077B9

Ala-D-Ala-OH

CAS: 3695-80-5

Ala-D-Ala-OH is an amide that is found in the wild-type strain of Streptococcus pneumoniae. It is a ligase inhibitor with a molecular weight of 164.2 daltons and a pK of 10.3. The inhibition of the ligase by Ala-D-Ala-OH may be due to its ability to bind to the penicillin binding protein and inhibit intramolecular hydrogen bonding, which is necessary for peptide bond formation. Ala-D-Ala-OH can also bind to other molecules that have an amide group, such as vancomycin, which has shown anti bacterial activity against Gram positive bacteria.

Formula: C₆H₁₂N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 160.17 g/mol

Ref: 3D-FA48629

Ala-D-Ala-OH

CAS: 3695-80-5

Formula: C₆H₁₂N₂O₃

Purity: 97%

Color and Shape: Liquid, No data available.

Molecular weight: 160.173

Ref: 10-F492885