CAS 36951-72-1

5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate)

Description:

5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate) is a cationic porphyrin compound characterized by its complex structure, which includes a porphyrin core substituted with four 1-methyl-4-pyridinium groups. This substitution imparts significant solubility in polar solvents, making it useful in various applications, including photodynamic therapy and as a dye in biological studies. The tetra(p-toluenesulfonate) component enhances its solubility and stability in aqueous environments. The compound exhibits strong absorption in the visible region of the electromagnetic spectrum, particularly in the Soret and Q bands, which is typical for porphyrins, allowing it to be utilized in light-harvesting and photochemical processes. Additionally, its cationic nature can facilitate interactions with negatively charged biological molecules, enhancing its potential for therapeutic applications. Overall, this compound is notable for its unique structural features and versatile applications in both research and clinical settings.

Formula: C₄₄H₃₈N₈·4C₇H₇O₃S

InChI: InChI=1S/C44H37N8.C7H8O3S/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31;1-6-2-4-7(5-3-6)11(8,9)10/h5-28H,1-4H3,(H,45,46,47,48);2-5H,1H3,(H,8,9,10)/q+3;/b41-33-,41-34?,42-35-,42-37?,43-36-,43-38?,44-39-,44-40?;

InChI key: InChIKey=LZWDWCBCNUIVSC-JJUIXLEHSA-N

SMILES: C[N+]=1C=CC(C=2C=3NC(=CC3)C(=C4N=C(C=C4)C(=C5NC(=C(C6=NC2C=C6)C=7C=C[N+](C)=CC7)C=C5)C=8C=C[N+](C)=CC8)C=9C=C[N+](C)=CC9)=CC1.S(=O)(=O)([O-])C1=CC=C(C)C=C1

Synonyms:

• 4,4',4'',4'''-Porphyrin-5,10,15,20-Tetrayltetrakis(1-Methylpyridinium)
• 5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate)
• 5,10,15,20-Tetrakis(1-methyl-4-pyridyl)-21H,23H-porphine tetra-p-tosylate
• 5,10,15,20-Tetrakis(1-methylpyridinium-4-yl)porphyrin tetra(p-toluenesulfonate)
• 5,10,15,20-Tetrakis(1-methylpyridinium-4-yl)porphyrin tetratosylate
• 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphine tetrakis(p-toluenesulfonate)
• 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphyrin tetrakis(p-toluenesulfonate)
• 5,10,15,20-tetrakis(1-methyl-4-pyridyl)-21H,23H-P
• Pyridinium, 4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[1-methyl-, 4-methylbenzenesulfonate (1:4)
• Pyridinium, 4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[1-methyl-, salt with 4-methylbenzenesulfonic acid (1:4)
• TMPyP 4 4-methylbenzenesulfonate
• TMPyP 4 tosylate
• TMPyP [=alpha,,gamma,delta-Tetrakis(1-methylpiridinium-4-yl)porphine p-toluenesulfonate]
• TMPyP4 tetra(p-toluene sulfonate)
• Tetrakismethylpiridiniumylporphine
• Tmp 1363
• Tppt 4
• meso-Tetra(N-methyl-4-pyridinium)porphyrin tetratoluene-p-sulfonate
• meso-Tetrakis(1-methyl-4-pyridyl)porphyrin tetra(p-tosylate)
• meso-Tetrakis(1-methylpyridinium-4-yl)porphine p-toluenesulfonate
• meso-Tetrakis(N-methylpyridinium-4-yl)porphine tetratosylate

TMPyP [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]

CAS: 36951-72-1

Formula: C₇₂H₆₆N₈O₁₂S₄

Purity: >98.0%(N)

Color and Shape: Dark red to Dark purple to Dark blue powder to crystal

Molecular weight: 1,363.60

Ref: 3B-A5014

Tmpyp

CAS: 36951-72-1

Formula: C₇₂H₇₄N₈O₁₂S₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 1371.6644

Ref: IN-DA003M8G

TMPyP4 tosylate

CAS: 36951-72-1

TMPyP4 tosylate

Purity: ≥98%

Molecular weight: 1363.6g/mol

Ref: 54-BUP11370

5,10,15,20-Tetrakis(1-Methyl-4-Pyridinio)Porphyrin Tetra(P-Toluenesulfonate)

CAS: 36951-72-1

5,10,15,20-Tetrakis(1-Methyl-4-Pyridinio)Porphyrin Tetra(P-Toluenesulfonate)

Purity: 98%

Molecular weight: 1,363.60g/mol

Ref: 54-OR1011741

meso-Tetra (N-methyl-4-pyridyl) porphine tetra tosylate

CAS: 36951-72-1

Formula: C₇₂H₆₆N₈O₁₂S₄

Purity: >90%

Molecular weight: 1363.61

Ref: FT-TMP-1363

TMPyP4 tosylate

CAS: 36951-72-1

TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.

Formula: C₇₂H₆₆N₈O₁₂S₄

Purity: 98.61% - 99.85%

Color and Shape: Solid

Molecular weight: 1363.6

Ref: TM-T13174

TMPyP4

Controlled Product

CAS: 36951-72-1

Stability Hygroscopic, Light Sensitive
Applications TMPyP4 is a potent inhibitor of telomerase activity.
References Calvo, E. P., et al.: Mol. Biochem. Parasitol., 207, 33 (2016)

Formula: C₇₂H₆₆N₈O₁₂S₄

Color and Shape: Neat

Molecular weight: 1363.6

Ref: TR-T460010

TMPyP4 tosylate

CAS: 36951-72-1

TMPyP4 tosylate is a chemical compound that is used in the treatment of bacterial infections. It is an active substance that can be used to prepare stable complexes with amines, which are then activated by intestinal enzymes. TMPyP4 tosylate has been shown to have binding activities towards telomeric DNA and gram-negative bacteria. This drug has been found to inhibit the growth of typhimurium, a gram-negative bacterium, by interacting with its ribosomal RNA and inhibiting protein synthesis.

Formula: C₇₂H₆₆N₈O₁₂S₄

Purity: Min. 95%

Molecular weight: 1,363.6 g/mol

Ref: 3D-LBA95172