CAS 370-86-5
:FCCP
Description:
FCCP, or carbonyl cyanide p-trifluoromethoxyphenylhydrazone, is a chemical compound known for its role as a protonophore and uncoupler of oxidative phosphorylation in biological systems. It is characterized by its ability to disrupt the proton gradient across mitochondrial membranes, thereby inhibiting ATP synthesis while allowing electron transport to continue. This property makes FCCP a valuable tool in biochemical research, particularly in studies related to cellular respiration and energy metabolism. The compound is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol, but has limited solubility in water. FCCP is also known for its high potency and effectiveness at low concentrations, which necessitates careful handling and usage in laboratory settings. Due to its uncoupling activity, it can induce cellular stress responses, making it important to consider its effects on cell viability and function in experimental designs. Safety precautions should be taken when working with FCCP, as it is classified as a hazardous substance.
Formula:C10H5F3N4O
InChI:InChI=1S/C10H5F3N4O/c11-10(12,13)18-9-3-1-7(2-4-9)16-17-8(5-14)6-15/h1-4,16H
InChI key:InChIKey=BMZRVOVNUMQTIN-UHFFFAOYSA-N
SMILES:O(C(F)(F)F)C1=CC=C(NN=C(C#N)C#N)C=C1
Synonyms:- 2-[2-[4-(Trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile
- FCCP
- Propanedinitrile, 2-[2-[4-(trifluoromethoxy)phenyl]hydrazinylidene]-
- Propanedinitrile, [[4-(trifluoromethoxy)phenyl]hydrazono]-
- Mesoxalonitrile, [p-(trifluoromethoxy)phenyl]hydrazone
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Found 9 products.
Carbonyl Cyanide 4-(Trifluoromethoxy)phenylhydrazone
CAS:Formula:C10H5F3N4OPurity:>95.0%(GC)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:254.17Propanedinitrile, [[4-(trifluoromethoxy)phenyl]hydrazono]-
CAS:Formula:C10H5F3N4OPurity:95%Color and Shape:SolidMolecular weight:254.1681FCCP
CAS:<p>FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler.</p>Formula:C10H5F3N4OPurity:98% - 99.65%Color and Shape:White SolidMolecular weight:254.172-{2-[4-(Trifluoromethoxy)phenyl]hydrazono}malononitrile
CAS:<p>2-{2-[4-(Trifluoromethoxy)phenyl]hydrazono}malononitrile</p>Purity:95%Color and Shape:Dark Yellow PowderMolecular weight:254.17g/molCarbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
CAS:<p>Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP) is a pharmacological agent that is used to study the mechanisms of neuronal death and mitochondrial dysfunction. FCCP is reactive with cellular components, such as proteins and nucleic acids. It also affects mitochondrial membrane potential, energy metabolism, and synchronous fluorescence in human cells. The reactive effects of FCCP are due to its ability to reduce intracellular dinucleotide phosphate (DNP). DNP binds to the electron transport chain, which leads to the production of reactive oxygen species that disrupt cellular physiology.</p>Formula:C10H5F3N4OPurity:Min. 97 Area-%Color and Shape:White To Yellow To Green-Yellow SolidMolecular weight:254.17 g/molCarbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
CAS:<p>M04086 - Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone</p>Formula:C10H5F3N4OPurity:98%Color and Shape:Solid, PowderMolecular weight:254.172
![Propanedinitrile, [[4-(trifluoromethoxy)phenyl]hydrazono]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IMFB.jpg&w=3840&q=75)
![2-{2-[4-(Trifluoromethoxy)phenyl]hydrazono}malononitrile](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FPC0578.jpg&w=3840&q=75)
