CAS 37051-05-1

(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Description:

The chemical substance known as "(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid," with the CAS number 37051-05-1, is a complex bicyclic compound featuring a thiazolidine ring structure. This compound is characterized by the presence of multiple functional groups, including an aminocarbonyl group, a carboxylic acid, and an oxo group, which contribute to its biological activity. The thienyl acetyl moiety suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Its stereochemistry, indicated by the (6R,7R) configuration, is crucial for its pharmacological properties, as stereoisomers can exhibit different biological activities. The compound's unique structure may confer specific mechanisms of action, potentially making it a candidate for therapeutic applications. Additionally, its solubility, stability, and reactivity are influenced by the functional groups present, which are important considerations in drug development and formulation.

Formula: C₁₅H₁₅N₃O₆S₂

InChI: InChI=1S/C15H15N3O6S2/c16-15(23)24-5-7-6-26-13-10(12(20)18(13)11(7)14(21)22)17-9(19)4-8-2-1-3-25-8/h1-3,10,13H,4-6H2,(H2,16,23)(H,17,19)(H,21,22)/t10-,13-/m1/s1

InChI key: InChIKey=YZKJQBUBQFJLMF-ZWNOBZJWSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(CC3=CC=CS3)=O)C2=O)(SCC1COC(N)=O)[H]

Synonyms:

• (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6S,7S)-3-(carbamoyloxymethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, (6R-trans)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, (6R,7R)-
• Cephalosporin 87/359
• (6R-trans)-3-((Carbamoyloxy)methyl)-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid

Cefoxitin Impurity 2

CAS: 37051-05-1

Formula: C₁₅H₁₅N₃O₆S₂

Molecular weight: 397.42

Ref: 4Z-C-156011

Cephalosporin 87/359(Cefoxitin Impurity H)

Controlled Product

CAS: 37051-05-1

Applications Cephalosporin 87/359 is an impurity of Cefoxitin (C243190). Cefoxitin is a semi-synthetic antibiotic derived from Cephamycin C, possessing high resistance to β-lactamase inactivation. An antibacterial.
References Wallick, H., et al.: Antimicrob. Agents Chemother., 5, 25 (1974), Brenner, G.S., et al.: Anal. Profiles Drug Subs., 11, 169 (1982),

Formula: C₁₅H₁₅N₃O₆S₂

Color and Shape: Neat

Molecular weight: 397.426

Ref: TR-C243110

Cephalosporin 87/359(cefoxitin impurity H)

CAS: 37051-05-1

Cephalosporin 87/359 (cefoxitin impurity H) is an analytical reference standard, which is a secondary metabolite that can arise during the synthesis or degradation of the cephalosporin antibiotic, cefoxitin. It is sourced from chemical synthesis processes where isolation and purification of impurities are essential for ensuring the efficacy and safety of pharmaceutical products. The mode of action of this impurity is not therapeutic but crucial for analytical purposes, serving as a comparator to detect and quantify potential contaminants in cefoxitin production.

Formula: C₁₅H₁₅N₃O₆S₂

Purity: Min. 95%

Molecular weight: 397.40 g/mol

Ref: 3D-MBA05105

Cefoxitin EP Impurity H

CAS: 37051-05-1

Formula: C₁₅H₁₅N₃O₆S₂

Molecular weight: 397.42

Ref: ST-EA-CP-C125007