CAS 37052-78-1

2-Mercapto-5-methoxybenzimidazole

Description:

2-Mercapto-5-methoxybenzimidazole is an organic compound characterized by its benzimidazole core, which features a mercapto (-SH) group and a methoxy (-OCH3) substituent. This compound typically appears as a solid and is known for its potential applications in pharmaceuticals and biochemistry, particularly due to its thiol group, which can participate in various chemical reactions, including redox processes. The presence of the methoxy group can influence the compound's solubility and reactivity, making it a subject of interest in medicinal chemistry. Additionally, compounds like 2-Mercapto-5-methoxybenzimidazole may exhibit biological activity, including antioxidant properties, which can be beneficial in therapeutic contexts. Its molecular structure allows for interactions with biological macromolecules, potentially leading to various biological effects. As with many chemical substances, safety and handling precautions should be observed, as thiol-containing compounds can be reactive and may have specific toxicity profiles.

Formula: C₈H₈N₂OS

InChI: InChI=1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)10-8(12)9-6/h2-4H,1H3,(H2,9,10,12)

InChI key: InChIKey=KOFBRZWVWJCLGM-UHFFFAOYSA-N

SMILES: S=C1NC=2C(=CC(OC)=CC2)N1

Synonyms:

• 1,3-Dihydro-5-methoxybenzimidazole-2-thione
• 1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione
• 2-Mercapto-5-Methoxy Benzimidazole
• 2-Mercapto-5-Methoxy-1H-Benzimidazole
• 2-Thio-5-methoxy-1H-benzimidazole
• 2H-Benzimidazole-2-thione, 1,3-dihydro-5-methoxy-
• 5-Methoxy-1,3-Dihydro-Benzoimidazole-2-Thione
• 5-Methoxy-1,3-dihydro-benzimidazol-2-thion
• 5-Methoxy-1H-Benzo[D]Imidazole-2-Thiol
• 5-Methoxy-1H-benzo[d]imidazole-2(3H)-thione
• 5-Methoxy-1H-benzoimidazole-2-thiol
• 5-Methoxy-2-Thiobenzimidazole
• 5-Methoxy-2-benzimidazolethiol
• 5-Methoxy-2-mercaplobenzinidazole
• 5-Methoxy-2-mercapto-1H-benzimidazole
• 5-Methoxy-2-mercaptobenzimidazole
• 5-Methoxybenzimidazole-2-thiol
• 5-Methoxybenzimidazolin-2-Mercapto
• 5-Methoxybenzimidazolin-2-Thione
• 5-methoxy-1H-benzimidazole-2-thiol
• 5-methyoxy-2-mercapto Benzimidazole
• Esomeprazole EP impurities
• Methoxy-2-mercaptobenzimidazole,5-
• Timtec-Bb Sbb000219

2-Mercapto-5-methoxybenzimidazole

CAS: 37052-78-1

Formula: C₈H₈N₂OS

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 180.23

Ref: 3B-M1256

2-Mercapto-5-methoxybenzimidazole, 99%

CAS: 37052-78-1

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfo

Formula: C₈H₈N₂OS

Purity: 99%

Color and Shape: Powder, Pale cream to cream

Molecular weight: 180.23

Ref: 02-B20570

Omeprazole Related Compound B (5-Methoxy-1H-benzimidazol-2-thiol)

CAS: 37052-78-1

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₈H₈N₂OS

Color and Shape: White Off-White Powder

Molecular weight: 180.03573

Ref: 45-1478480

5-Methoxy-2-Benzimidazolethiol

CAS: 37052-78-1

Formula: C₈H₈N₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 180.2269

Ref: IN-DA007CC0

2-Mercapto-5-methoxy-1H-benzimidazole

CAS: 37052-78-1

Formula: C₈H₈N₂OS

Purity: ≥ 98.0%

Color and Shape: White to beige or light brown powder

Molecular weight: 180.23

Ref: 7W-GK4719

Omeprazole EP Impurity A (Omeprazole USP Related Compound B, Esomeprazole EP Impurity A)

CAS: 37052-78-1

Formula: C₈H₈N₂OS

Color and Shape: Off-White Solid

Molecular weight: 180.23

Ref: 4Z-O-0232

5-Methoxy-1H-benzimidazole-2-thiol

Controlled Product

CAS: 37052-78-1

Formula: C₈H₈N₂OS

Color and Shape: Neat

Molecular weight: 180.23

Ref: 86-MM0095.03

5-Methoxy-2-thio-1H-benzimidazole

CAS: 37052-78-1

5-Methoxy-2-thio-1H-benzimidazole

Formula: C₈H₈N₂OS

Purity: 98%

Color and Shape: faint beige to faint yellow powder

Molecular weight: 180.23g/mol

Ref: 54-OR9581

5-Methoxy-2-mercaptobenzimidazole

Controlled Product

CAS: 37052-78-1

Impurity Esomeprazol EP Impurity A/ Omeprazole EP Impurity A
Applications 5-Methoxy-2-mercaptobenzimidazole (Esomeprazol EP Impurity A) is used in the synthesis of COX-2 inhibitors
References Frechette, S., et al.: Bioorg. Med. Chem. Lett., 18, 1502 (2008), Zhang, R., et al.: Eur. J. Med. Chem., 44, 3771 (2009),

Formula: C₈H₈N₂OS

Color and Shape: Beige

Molecular weight: 180.23

Ref: TR-M262760

Esomeprazole EP Impurity A

CAS: 37052-78-1

Formula: C₈H₈N₂OS

Molecular weight: 180.23

Ref: ST-EA-CP-E14001

Omeprazole EP Impurity A

CAS: 37052-78-1

Formula: C₈H₈N₂OS

Molecular weight: 180.22

Ref: ST-EA-CP-O9001

5-Methoxy-2-mercaptobenzimidazole

CAS: 37052-78-1

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Formula: C₈H₈N₂OS

Purity: Min. 99.00 Area-%

Molecular weight: 180.23 g/mol

Ref: 3D-W-202531

5-Methoxy-2-mercaptobenzimidazole

CAS: 37052-78-1

5-Methoxy-2-mercaptobenzimidazole is a chiral compound that can be used as a reagent for the preparation of phosphate buffer. It reacts with tyrosinase to form a yellow product and phosphotungstic acid. The reaction solution contains sodium citrate, which is used to adjust the pH. 5-Methoxy-2-mercaptobenzimidazole is a benzimidazole derivative and its protonated form has an affinity for hydrogen bond formation. The magnesium salt in this reaction solution acts as an organic solvent. This analytical method has detection sensitivity at 10 ppm.

Formula: C₈H₈N₂OS

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 180.23 g/mol

Ref: 3D-FM00167

5-Methoxy-1H-benzo[d]imidazole-2-thiol

CAS: 37052-78-1

Formula: C₈H₈N₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 180.23

Ref: 10-F234441