CAS 37091-65-9

Azlocillin sodium

Description:

Azlocillin sodium is a semisynthetic penicillin antibiotic that exhibits broad-spectrum antibacterial activity, particularly against Gram-negative bacteria. It is characterized by its ability to inhibit bacterial cell wall synthesis, which is a common mechanism of action among beta-lactam antibiotics. Azlocillin is often used in clinical settings to treat infections caused by susceptible organisms, including those resistant to other penicillins. The sodium salt form enhances its solubility in aqueous solutions, making it suitable for intravenous administration. Azlocillin is generally stable in the presence of certain beta-lactamases, although it may be susceptible to others. Its pharmacokinetics include a relatively short half-life, necessitating multiple doses for effective therapeutic levels. Side effects may include allergic reactions, gastrointestinal disturbances, and potential impacts on renal function. As with all antibiotics, appropriate susceptibility testing is essential to ensure its effectiveness against specific pathogens. Overall, Azlocillin sodium represents an important option in the arsenal of antibiotics used to combat bacterial infections.

Formula: C₂₀H₂₃N₅O₆S·Na

InChI: InChI=1S/C20H23N5O6S.Na/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30;/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29);/t11-,12-,13+,16-;/m1./s1

InChI key: InChIKey=FUHFQQPUHNRIQM-XFAPPKAWSA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](NC([C@H](NC(=O)N3C(=O)NCC3)C4=CC=CC=C4)=O)C2=O)(SC1(C)C)[H].[Na]

Synonyms:

• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2S)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]-2-phenylacetyl]amino]-, sodium salt (1:1), (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-, monosodium salt, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[[[(2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-, monosodium salt, [2S-[2α,5α,6β(S*)]]-
• Azlin
• Azlocillin sodium salt
• Monosodium azlocillin
• Securopen
• Sodium azlocillin
• sodium (2R,5S,6S)-3,3-dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2S)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Azlocillin sodium salt

CAS: 37091-65-9

Formula: C₂₀H₂₂N₅NaO₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 483.4733

Ref: IN-DA00ILQK

Azlocillin sodium salt

CAS: 37091-65-9

Azlocillin sodium salt

Purity: ≥95%

Molecular weight: 483.47g/mol

Ref: 54-BUP17685

Azlocillin sodium salt

CAS: 37091-65-9

Formula: C₂₀H₂₂N₅O₆SNa

Purity: ≥ 90.0% (dried basis)

Color and Shape: White or almost white powder

Molecular weight: 483.47

Ref: 7W-GA9075

Azlocillin Sodium

CAS: 37091-65-9

Azlocillin Sodium

Purity: 98%

Molecular weight: 483.47g/mol

Ref: 54-OR1026697

Azlocillin sodium salt

CAS: 37091-65-9

Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics

Formula: C₂₀H₂₂N₅NaO₆S

Purity: 97.63% - 98.302%

Color and Shape: Solid

Molecular weight: 483.47

Ref: TM-T0049

Azlocillin Sodium Salt

Controlled Product

CAS: 37091-65-9

Stability Hygroscopic
Applications Azlocillin Sodium Salt is the sodium salt form of Azlocillin which is a semisynthetic ampicillin-derived acylureido penicillin with antibacterial activity against a broad range of bacteria including haemophilus influenzae, bacteroides and pseudomonas aeruginosa.
References Reeves, D., et al.: Arzneimittel-Forschung, 29, 1920 (1979); Opalchenova, G., et al.: Int. J. Pharm.,153, 263 (1997);

Formula: C₂₀H₂₃N₅O₆S(Na)

Color and Shape: Off White Powder

Molecular weight: 461.492299

Ref: TR-A930000

Azlocillin sodium salt

CAS: 37091-65-9

Azlocillin sodium salt is a penicillin antibiotic and is used for the treatment of bacterial infections. It inhibits bacterial cell wall synthesis.

Formula: C₂₀H₂₃N₅O₆SNa

Purity: Min. 90 Area-%

Color and Shape: White Powder

Molecular weight: 484.48 g/mol

Ref: 3D-AA33382

Azlocillin Sodium Salt

CAS: 37091-65-9

Formula: C₂₀H₂₂N₅O₆SNa

Molecular weight: 460.49 : 23.0

Ref: ST-EA-CP-A59031