CAS 371-42-6

4-Fluorobenzenethiol

Description:

4-Fluorobenzenethiol, also known as para-fluorothiophenol, is an organofluorine compound characterized by the presence of a fluorine atom and a thiol (-SH) group attached to a benzene ring. Its molecular formula is C6H5FOS, and it features a fluorine substituent at the para position relative to the thiol group. This compound is typically a colorless to pale yellow liquid with a distinct odor, indicative of its thiol functionality. 4-Fluorobenzenethiol is known for its reactivity, particularly in nucleophilic substitution reactions, due to the electron-withdrawing effect of the fluorine atom, which enhances the nucleophilicity of the thiol group. It is used in various applications, including organic synthesis and as a building block in the preparation of more complex molecules. Additionally, it may exhibit biological activity, making it of interest in medicinal chemistry. Proper handling and storage are essential, as thiols can be malodorous and may pose health risks if inhaled or ingested.

Formula: C₆H₅FS

InChI: InChI=1S/C6H5FS/c7-5-1-3-6(8)4-2-5/h1-4,8H

InChI key: InChIKey=OKIHXNKYYGUVTE-UHFFFAOYSA-N

SMILES: FC1=CC=C(S)C=C1

Synonyms:

• (4-Fluorophenyl)thiol
• 4-Fluoro Thiophenol
• 4-Fluorobenzene-1-thiol
• 4-Fluorobenzenethiol
• 4-Fluorobenzenethiolate
• 4-Fluorophenyl mercaptan
• Benzenethiol, 4-fluoro-
• Benzenethiol, p-fluoro-
• Fluorothiophenol2
• NSC 77081
• p-Fluorobenzenethiol

4-Fluorothiophenol, 97%

CAS: 371-42-6

It is used in the synthesis of Bicalutamide, an anti-cancer drug. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU refere

Formula: C₆H₅FS

Purity: 97%

Color and Shape: Liquid, Clear colorless to pale yellow

Molecular weight: 128.16

Ref: 02-A17600

4-Fluorothiophenol

CAS: 371-42-6

Formula: C₆H₅FS

Purity: 95%

Color and Shape: Liquid

Molecular weight: 128.1673

Ref: IN-DA00341P

4-Fluorothiophenol

CAS: 371-42-6

Formula: C₆H₅FS

Molecular weight: 128.17

Ref: 7W-GK7379

4-Fluorothiophenol

CAS: 371-42-6

4-Fluorothiophenol

Formula: C₆H₅FS

Purity: 95%

Color and Shape: clear. light red/pink liquid

Molecular weight: 128.17g/mol

Ref: 54-PC4300

4-Fluorobenzenethiol

CAS: 371-42-6

Formula: C₆H₅FS

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 128.16

Ref: 3B-F0393

4-Fluorothiophenol

CAS: 371-42-6

Color and Shape: Neat

Ref: 86-MM0894.17

4-Fluorothiophenol

CAS: 371-42-6

Formula: C₆H₅FS

Purity: 95%

Color and Shape: Liquid, Clear

Molecular weight: 128.16

Ref: 10-F001625

4-Fluorothiophenol

Controlled Product

CAS: 371-42-6

Applications 4-Fluorothiophenol is primarily used in wet chemistry as a capping ligand for various metal nanostructures so that they don’t aggregate in solution. 4-Fluorothiophenol is also capable of creating a self-assembled monolayer, which is used to improve the interface properties of metal electrodes with hydrophobic layers.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bakr, O., et al.: Angew. Chem., 121, 6035 (2009); Boev, V., et al.: Solid State Sci., 8, 50 (2006); Li, G., et al.: Mat. Chem. Phys., 129, 1011 (2011); Yang, L., et al.: Appl. Surf. Sci., 254, 5055 (2008)

Formula: C₆H₅FS

Color and Shape: Neat

Molecular weight: 128.17

Ref: TR-F489550

4-Fluorothiophenol

CAS: 371-42-6

4-Fluorothiophenol is a reactive chemical that can be used as a monomer for the synthesis of polymers. It has been shown to polymerize with acrylonitrile and methacrylate in the presence of an initiator to form polyacrylonitrile and polymethacrylate, respectively. 4-Fluorothiophenol reacts with unsaturated fatty acids to form thiolates, which are useful intermediates in organic synthesis. 4-Fluorothiophenol also reacts with sulfur transfer agents such as thiourea or mercaptoethanol, leading to S-sulfides that are useful intermediates in organic synthesis. These reactions can be followed by kinetic energy spectroscopy (photoelectron) and nuclear magnetic resonance spectroscopy (NMR). 4-Fluorothiophenol has been shown to undergo intramolecular hydrogen transfer reactions with second order rate constants ranging from

Formula: C₆H₅FS

Purity: Min. 95%

Molecular weight: 128.17 g/mol

Ref: 3D-FF34648