Ethyl {2-methyl-3-[2-(naphtho[2,1-b]furan-2-ylcarbonyl)carbohydrazonoyl]-1H-indol-1-yl}acetate, identified by its CAS number 371135-20-5, is a complex organic compound characterized by its intricate molecular structure, which includes an indole moiety, a naphtho[2,1-b]furan unit, and a hydrazone linkage. This compound typically exhibits properties associated with both aromatic and heterocyclic compounds, such as stability and potential biological activity. The presence of the ethyl acetate group suggests it may have moderate solubility in organic solvents, while the hydrazone functionality could impart reactivity towards various nucleophiles. Additionally, the naphtho[2,1-b]furan component may contribute to its photophysical properties, making it of interest in fields such as organic electronics or medicinal chemistry. Overall, this compound's unique structure may lead to diverse applications, particularly in drug development or as a synthetic intermediate in organic synthesis. Further studies would be necessary to elucidate its specific reactivity and potential applications.

STK899704 is a novel tubulin inhibitor, preventing the polymerization of purified tubulin in vitro and depolymerizing microtubule in cultured cells leading to mitotic arrest, associated with increased Cdc25C phosphorylation and the accumulation of both cyclin B1 and polo-like kinase 1 (Plk1), and apoptosis.

ethyl {2-methyl-3-[2-(naphtho[2,1-b]furan-2-ylcarbonyl)carbohydrazonoyl]-1H-indol-1-yl}acetate

371135-20-5: Ethyl {2-methyl-3-[2-(naphtho[2,1-b]furan-2-ylcarbonyl)carbohydrazonoyl]-1H-indol-1-yl}acetate, identified by its CAS number 371135-20-5, is a complex organic compound characterized by its intricate molecular structure, which includes an indole moiety, a naphtho[2,1-b]furan unit, and a hydrazone linkage. This compound typically exhibits properties associated with both aromatic and heterocyclic compounds, such as stability and potential biological activity. The presence of the ethyl acetate group suggests it may have moderate solubility in organic solvents, while the hydrazone functionality could impart reactivity towards various nucleophiles. Additionally, the naphtho[2,1-b]furan component may contribute to its photophysical properties, making it of interest in fields such as organic electronics or medicinal chemistry. Overall, this compound's unique structure may lead to diverse applications, particularly in drug development or as a synthetic intermediate in organic synthesis. Further studies would be necessary to elucidate its specific reactivity and potential applications.

STK899704 inhibits tubulin, blocks its polymerization in vitro, and causes mitotic arrest by depolymerizing microtubules in cells.

CAS 371135-20-5

ethyl {2-methyl-3-[2-(naphtho[2,1-b]furan-2-ylcarbonyl)carbohydrazonoyl]-1H-indol-1-yl}acetate

STK899704

Ref: TM-T28868