CAS 37115-43-8

α-Hydroxyalprazolam

Description:

α-Hydroxyalprazolam is a chemical compound that belongs to the benzodiazepine class of medications, which are primarily used for their anxiolytic, sedative, and hypnotic properties. It is a derivative of alprazolam, characterized by the presence of a hydroxyl group at the alpha position of the benzodiazepine ring. This modification can influence its pharmacological activity and metabolism. The compound is typically white to off-white in appearance and is soluble in organic solvents. Its mechanism of action involves the enhancement of GABA (gamma-aminobutyric acid) activity at the GABA-A receptor, leading to increased inhibitory neurotransmission in the central nervous system. α-Hydroxyalprazolam is often studied for its potential effects on anxiety and panic disorders, as well as its pharmacokinetic profile, which may differ from that of its parent compound, alprazolam. As with other benzodiazepines, it is important to consider the potential for dependence and withdrawal symptoms associated with its use.

Formula: C₁₇H₁₃ClN₄O

InChI: InChI=1S/C17H13ClN4O/c18-12-6-7-14-13(8-12)17(11-4-2-1-3-5-11)19-9-15-20-21-16(10-23)22(14)15/h1-8,23H,9-10H2

InChI key: InChIKey=ZURUZYHEEMDQBU-UHFFFAOYSA-N

SMILES: C(O)C=1N2C=3C(C(=NCC2=NN1)C4=CC=CC=C4)=CC(Cl)=CC3

Synonyms:

• (8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl)methanol
• 1-Hydroxyalprazolam
• 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine-1-methanol, 8-chloro-6-phenyl-
• 6-Phenyl-8-chloro-4H-s-triazolo[4,3-a]benzodiazepine-1-methanol
• 8-Chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-1-methanol
• U 40125
• alpha-Hydroxyalprazolam
• α-Hydroxyalprazolam

α-Hydroxyalprazolam

Controlled Product

CAS: 37115-43-8

Color and Shape: Neat

Ref: LP-ALP-536-FB-10

α-Hydroxyalprazolam, 1mg/ml in Methanol

Controlled Product

CAS: 37115-43-8

Color and Shape: Single Solution

Ref: LP-ALP-536-FB-1LM

α-Hydroxyalprazolam, 0.1mg/ml in Methanol

Controlled Product

CAS: 37115-43-8

Color and Shape: Single Solution

Ref: LP-ALP-536-FB-0.1LM

α-Hydroxyalprazolam 1.0 mg/ml in Methanol

CAS: 37115-43-8

Color and Shape: Single Solution

Ref: 61-AMP0136.02-01

α-Hydroxyalprazolam 0.1 mg/ml in Methanol

Controlled Product

CAS: 37115-43-8

Color and Shape: Single Solution

Ref: 61-AMP0136.02-02

α-Hydroxyalprazolam

Controlled Product

CAS: 37115-43-8

Formula: C₁₇H₁₃ClN₄O

Color and Shape: Neat

Molecular weight: 324.76

Ref: 86-MM0136.02

1-Hydroxy Alprazolam

Controlled Product

CAS: 37115-43-8

Formula: C₁₇H₁₃ClN₄O

Color and Shape: Neat

Molecular weight: 324.76

Ref: TR-H761500

1-Hydroxy Alprazolam-13C4

Controlled Product

CAS: 37115-43-8

Formula: C₁₃C₄H₁₃ClN₄O

Color and Shape: Neat

Molecular weight: 328.73

Ref: TR-H761503

α-Hydroxy alprazolam

CAS: 37115-43-8

α-Hydroxy alprazolam (U 40125), the primary metabolite of α-Hydroxy alprazolam, possesses pharmacological activity accounting for 60% of that of Alprazolam.

Formula: C₁₇H₁₃ClN₄O

Color and Shape: Solid

Molecular weight: 324.76

Ref: TM-T201680