CAS 3717-38-2: 1-(Methylamino)adamantane

Description: 1-(Methylamino)adamantane, also known as memantine, is a chemical compound characterized by its adamantane structure, which consists of a fused polycyclic framework. This compound features a methylamino group attached to the adamantane core, contributing to its pharmacological properties. Memantine is primarily recognized for its role as an NMDA receptor antagonist, which is significant in the treatment of neurodegenerative conditions, particularly Alzheimer's disease. The compound exhibits moderate lipophilicity, allowing it to cross the blood-brain barrier effectively. Its mechanism of action involves the modulation of glutamatergic neurotransmission, which is crucial for cognitive functions. Memantine is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. The substance is generally well-tolerated, with a side effect profile that includes dizziness, headache, and constipation. Its therapeutic use underscores the importance of understanding the interactions of small molecules with neurotransmitter systems in the brain. Overall, 1-(Methylamino)adamantane represents a significant advancement in pharmacotherapy for cognitive disorders.

Formula: C₁₁H₁₉N

InChI: InChI=1S/C11H19N/c1-12-11-5-8-2-9(6-11)4-10(3-8)7-11/h8-10,12H,2-7H2,1H3

InChI key: InChIKey=NZOLSRPWNVZXTK-UHFFFAOYSA-N

SMILES: N(C)C12CC3CC(CC(C3)C1)C2

Synonyms:

• 1-Adamantanamine, N-methyl-
• Brn 2348926
• Mrz 2/188
• N-(1-Adamantyl)-N-methylamine
• N-Methyl-1-adamantanamine
• N-Methyl-1-adamantylamine
• N-Methyladamantanamine
• N-Methyladamantine
• N-Methyltricyclo(3.3.1.1(sup 3,7))decan-1-amine
• N-Methyltricyclo[3.3.1.1^3,7]decan-1-amine
• N-methyltricyclo[3.3.1.1~3,7~]decan-1-amine
• Tricyclo(3.3.1.1(sup 3,7))decan-1-amine, N-methyl-
• Tricyclo[3.3.1.1^3,7]decan-1-amine, N-methyl-
• N-Methyltricyclo[3.3.1.13,7]decan-1-amine
• 1-(Methylamino)adamantane
• Tricyclo[3.3.1.13,7]decan-1-amine, N-methyl-

N-Methyladamantan-1-amine

CAS: 3717-38-2

• Formula: C₁₁H₁₉N
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 165.2753

N-Methyladamantan-1-amine

CAS: 3717-38-2

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 165.27999877929688

1-(Methylamino)adamantane

CAS: 3717-38-2

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• Formula: C₁₁H₁₉N
• Purity: Min. 95%
• Molecular weight: 165.28 g/mol