CAS 37318-34-6
:N-Acetylglucosamine 2-epimerase
Description:
N-Acetylglucosamine 2-epimerase, with the CAS number 37318-34-6, is an enzyme that plays a crucial role in carbohydrate metabolism, specifically in the interconversion of N-acetylglucosamine and N-acetylmannosamine. This enzyme catalyzes the epimerization at the C-2 position of N-acetylglucosamine, facilitating the conversion between these two amino sugars, which are important components of glycoproteins and glycolipids. N-Acetylglucosamine 2-epimerase is typically found in various organisms, including bacteria and mammals, and is involved in metabolic pathways that contribute to cell signaling and structural integrity of cellular components. The enzyme's activity is influenced by factors such as pH and temperature, and it may require specific cofactors for optimal function. Understanding the characteristics and mechanisms of this enzyme is essential for applications in biotechnology and medicine, particularly in the development of therapeutic agents targeting glycan-related processes.
Formula:Unspecified
Synonyms:- Epimerase, acylglucosamine 2-
- N-Acetylglucosamine 2-epimerase
- Acylglucosamine 2-epimerase
- N-Acylglucosamine-2-epimerase
- E.C. 5.1.3.8
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Found 1 products.
N-Acetyl-D-glucosamine 2-epimerase
CAS:<p>N-Acetyl-D-glucosamine 2-epimerase is an enzyme that catalyzes the conversion of N-acetyl D-glucosamine to N-acetyl D-mannosamine. This enzyme is a recombinant protein. It has been shown to be active against bacterial cells and has been used as a target for antibodies in research. The enzyme is insoluble at high concentrations, so it must be refolded before use. It is active in a denatured form, but can be made inactive by heat or other denaturing agents such as urea, guanidine hydrochloride, or sodium dodecyl sulfate (SDS). Refolding strategies include dilution, dialysis, or adsorption onto a solid support such as agarose beads.<br>!--</p>Purity:Min. 95%Color and Shape:Grey to brown solid.
