Pustulan, with the CAS number 37331-28-5, is a polysaccharide derived from the fungal cell wall component of certain fungi, particularly from the genus *Fusarium*. It is characterized by its structure, which consists of a linear chain of glucose units linked by β-(1→3) and β-(1→6) glycosidic bonds. This unique arrangement contributes to its solubility in water and its ability to form gels, making it useful in various applications, including food, pharmaceuticals, and cosmetics. Pustulan exhibits biocompatibility and biodegradability, which are advantageous for environmental sustainability. Additionally, it has been studied for its potential immunomodulatory effects, suggesting that it may play a role in enhancing the immune response. Its properties make it a subject of interest in research focused on natural polymers and their applications in drug delivery systems and tissue engineering. Overall, pustulan is a versatile biopolymer with promising applications across multiple fields due to its unique chemical characteristics.

Pustulan

37331-28-5: Pustulan, with the CAS number 37331-28-5, is a polysaccharide derived from the fungal cell wall component of certain fungi, particularly from the genus *Fusarium*. It is characterized by its structure, which consists of a linear chain of glucose units linked by β-(1→3) and β-(1→6) glycosidic bonds. This unique arrangement contributes to its solubility in water and its ability to form gels, making it useful in various applications, including food, pharmaceuticals, and cosmetics. Pustulan exhibits biocompatibility and biodegradability, which are advantageous for environmental sustainability. Additionally, it has been studied for its potential immunomodulatory effects, suggesting that it may play a role in enhancing the immune response. Its properties make it a subject of interest in research focused on natural polymers and their applications in drug delivery systems and tissue engineering. Overall, pustulan is a versatile biopolymer with promising applications across multiple fields due to its unique chemical characteristics.

Pustulan is a β-1,6-glucan isolated from Lasallia pustulata MW (20 kDa). It is recognized by the membrane bound Dectin-1, a C-type lectin-like pattern recognition receptor. Detection of β-glucans by Dectin-1 receptor leads to the CARD9-dependent activation of NF-κB and MAP kinases.  Studies have shown that pustulan can stimulate innate immune responses, inducing heat shock protein expression, eliciting phagocytosis, and production of pro-inflammatory cytokines.
The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.

CAS 37331-28-5

Pustulan

Pustulan

Ref: 3D-YP15423