CAS 37339-90-5

Lentinan

Description:

Lentinan is a polysaccharide derived from the shiitake mushroom, scientifically known as Lentinula edodes. It is classified as a beta-glucan, primarily composed of glucose units linked by beta-glycosidic bonds. Lentinan is notable for its immunomodulatory properties, which have been studied for potential therapeutic applications, particularly in enhancing immune responses against cancer and viral infections. It is often used as a dietary supplement and is recognized for its ability to stimulate the production of various immune cells, including macrophages and natural killer cells. In addition to its immunological benefits, lentinan exhibits antioxidant properties, contributing to its potential health benefits. The substance is typically administered in a purified form, and its efficacy can vary based on the dosage and method of administration. As a natural compound, lentinan is generally considered safe, although individuals should consult healthcare professionals before use, especially in conjunction with other treatments. Its CAS number, 37339-90-5, is used for identification in chemical databases and regulatory contexts.

Formula: Unspecified

InChI: InChI=1/C42H72O36/c43-1-8-15(48)22(55)25(58)37(69-8)66-6-13-20(53)32(28(61)36(65)68-13)75-40-29(62)33(18(51)11(4-46)72-40)77-41-30(63)34(19(52)12(5-47)73-41)78-42-31(64)35(76-39-27(60)24(57)17(50)10(3-45)71-39)21(54)14(74-42)7-67-38-26(59)23(56)16(49)9(2-44)70-38/h8-65H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22+,23+,24+,25-,26-,27-,28-,29-,30-,31-,32+,33+,34+,35+,36-,37-,38-,39+,40+,41+,42+/m1/s1

Synonyms:

• Biomoduline
• Bromoduline
• Drg-0171
• Lc-33
• Maitake Mushroom Extract
• Polysacharid lentinus edodes
• Shiitake Mushroom Extract
• beta-D-glucopyranosyl-(1->6)-[beta-D-glucopyranosyl-(1->3)-[beta-D-glucopyranosyl-(1->6)]-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranose
• Lentinan
• MeSH ID: D007912

Lentinan

CAS: 37339-90-5

Lentinan, isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.

Formula: C₄₂H₇₂O₃₆

Color and Shape: Solid

Molecular weight: 1153

Ref: TM-T5043

Lentinan

CAS: 37339-90-5

Formula: (C₄₂H₇₀O₃₅)n

Color and Shape: Tan to brown powder

Molecular weight: 1134.98

Ref: 7W-GP2959

Lentinan (Technical Grade)

Controlled Product

CAS: 37339-90-5

Applications Lentinan is an intravenous anti-tumor polysaccharide.
References Chihara, G., et al.: Cancer Res., 30, 2776 (1970); Ina, K., et al.: World J. Clin. Oncol., 2, 339 (2011)

Formula: (C₄₂H₇₀O₃₅)nH₂O

Color and Shape: Neat

Ref: TR-L329100

Lentinan

CAS: 37339-90-5

The polysaccharide Lentinan is isolated from the mushroom L. edodes (shitake mushroom). The primary structure is a β-(1–3)-glucose backbone with two (1–6)-β-glucose branches for each five glucose resiodues. Lentinan is clinically used for cancer treatment both in China and Japan. According to the clinical studies published in and outside of China, lentinan-based drugs are used for the treatment of various cancers, including lung, gastric, colorectal and other cancers. In addition, lentinan-based drugs are also used for treating HIV, hepatitis and malignant pleural effusion.

Color and Shape: Brown Powder

Ref: 3D-FL33321