CAS 3736-77-4

2,2′-Anhydrouridine

Description:

2,2′-Anhydrouridine, with the CAS number 3736-77-4, is a nucleoside analog derived from uridine. It is characterized by the absence of the hydroxyl group at the 2' position of the ribose sugar, which results in a unique structural configuration that influences its biochemical properties. This compound is typically a white to off-white solid and is soluble in water, making it suitable for various biological applications. 2,2′-Anhydrouridine is known for its role in nucleic acid research and has been studied for its potential antiviral and anticancer properties. Its structural modifications allow it to interact with nucleic acids and enzymes, potentially inhibiting certain biological processes. The compound's stability and reactivity can vary depending on environmental conditions, such as pH and temperature. Overall, 2,2′-Anhydrouridine serves as an important tool in molecular biology and medicinal chemistry, contributing to the understanding of nucleoside function and the development of therapeutic agents.

Formula: C₉H₁₀N₂O₅

InChI: InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1

InChI key: InChIKey=UUGITDASWNOAGG-CCXZUQQUSA-N

SMILES: O[C@H]1[C@]2([C@](N3C(O2)=NC(=O)C=C3)(O[C@@H]1CO)[H])[H]

Synonyms:

• (2R,3R,3aR,9aR)-3-hydroxy-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one
• (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidin-6-one
• (2R,3R,3aS,9aR)-3-hydroxy-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one
• 02,2-Cycloridine
• 2,2'-Anhydro-uridine
• 2,2'-O-Anhydro-(1-β-D-arabinofuranosyl)uracil
• 2,2-Anhydro-1-(b-D-Arabinofuranosyl) Uracil
• 2,2-Anhydrocytidine
• 2,2′-Anhydro(1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl)uracil
• 2,2′-Anhydro-1-β-<span class="text-smallcaps">D</span>-arabino-furanosyluracil
• 2,2′-Anhydro-N¹-(β-<span class="text-smallcaps">D</span>-arabinofuranosyl)uracil
• 2,2′-Anhydrouridine
• 2,2′-O-Cyclouridine
• 3-hydroxy-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one
• 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-
• 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, (2R,3R,3aS,9aR)-
• 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, [2R-(2α,3β,3aβ,9aβ)]-
• 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, stereoisomer
• Anhydro-U
• NSC 157148
• O²,2′-Anhydrouridine
• O²,2′-Cyclouridine
• β-<span class="text-smallcaps">D</span>-2′,2-O-Cycloarabinouridine

2,2'-O-Cyclouridine

CAS: 3736-77-4

Formula: C₉H₁₀N₂O₅

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 226.19

Ref: 3B-C2208

2,2'-Anhydro(1-β-D-arabinofuranosyl)uracil

CAS: 3736-77-4

Formula: C₉H₁₀N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 226.1861

Ref: IN-DA0039LN

2,2''-Anhydrouridine

CAS: 3736-77-4

Formula: C₉H₁₀N₂O₅

Molecular weight: 226.19

Ref: 7W-GN7704

2,2'-Anhydrouridine

CAS: 3736-77-4

2,2'-Anhydrouridine

Purity: ≥98%

Molecular weight: 226.19g/mol

Ref: 54-BUP17731

2,2'-O-Cyclouridine

CAS: 3736-77-4

2,2'-O-Cyclouridine

Purity: 98%

Molecular weight: 226.19g/mol

Ref: 54-OR1009951

Uridine Impurity 1

CAS: 3736-77-4

Formula: C₉H₁₀N₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 226.19

Ref: 4Z-U-0125

2,2'-Anhydrouridine

CAS: 3736-77-4

2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.

Formula: C₉H₁₀N₂O₅

Purity: 98.45%

Color and Shape: Solid

Molecular weight: 226.19

Ref: TM-T5981

2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil

CAS: 3736-77-4

Purity: 95.0%

Color and Shape: Solid, White powder

Molecular weight: 226.18800354003906

Ref: 10-F092305

2,2'-Anhydrouridine

CAS: 3736-77-4

The nucleophilic opening of 2,2'-Anhydrouridine represents a novel synthetic approach for elaborating the ring of nucleosides. For example, compounds such as 2-amino-, 2-fluoro- and 2-phenylseleno-2-deoxyuridines are prepared from the nucleophilic opening of 2,2'-Anhydrouridine.Â2,2'-Anhydrouridine inhibits uridine phosphorylase, a key enzyme targeted by some antitumor drugs.

Formula: C₉H₁₀N₂O₅

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 226.19 g/mol

Ref: 3D-NA05939

Uridine Impurity 7

CAS: 3736-77-4

Formula: C₉H₁₀N₂O₅

Molecular weight: 226.19

Ref: ST-EA-CP-U6025