CAS 3736-81-0
:Diloxanide furoate
Description:
Diloxanide furoate is an antiprotozoal agent primarily used in the treatment of intestinal amoebiasis caused by Entamoeba histolytica. It is a prodrug that is converted in the body to its active form, diloxanide, which exerts its therapeutic effects by inhibiting the growth of the amoeba. The compound is characterized by its chemical structure, which includes a furoate moiety, contributing to its solubility and bioavailability. Diloxanide furoate is typically administered orally and is known for its relatively low toxicity profile compared to other treatments for amoebiasis. It is often used in combination with other medications to enhance efficacy and reduce the risk of resistance. The substance is generally well-tolerated, with side effects being mild and infrequent. Its mechanism of action involves interference with the metabolic processes of the parasite, ultimately leading to its elimination from the host. As with any medication, it is essential to follow prescribed dosages and consult healthcare professionals regarding its use.
Formula:C14H11Cl2NO4
InChI:InChI=1/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3
InChI key:InChIKey=BDYYDXJSHYEDGB-UHFFFAOYSA-N
SMILES:N(C(C(Cl)Cl)=O)(C)C1=CC=C(OC(=O)C2=CC=CO2)C=C1
Synonyms:- 2,2-Dichloroacetamideo-4-N-methylphenyl 2-furoate
- 2-Furancarboxylic acid, 4-((dichloroacetyl)methylamino)phenyl ester
- 2-Furancarboxylic acid, 4-[(2,2-dichloroacetyl)methylamino]phenyl ester
- 2-Furoic acid, ester with 2,2-dichloro-4'-hydroxy-N-methylacetanilide
- 4-((Dichloroacetyl)methylamino)phenyl 2-furoate
- 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furancarboxylat
- 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furancarboxylat [IUPAC]
- 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furoat
- 4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furoat [IUPAC]
- 4-(N-Methyl-2,2-dichloroacetamideo)phenyl 2-furoate
- 4-Hydroxy-N-methyl dichloroacetanilide 2-furoate
- 4-[(Dichloroacetyl)(Methyl)Amino]Phenyl Furan-2-Carboxylate
- 8073 Cb
- Acetanilide, 2,2-dichloro-4′-hydroxy-N-methyl-, 2-furoate (ester)
- Amebiazol
- Cb 8073
- Dichlofurazol
- Diclofurazol
- Diloxanid furoate
- Entamide 2-furoate
- Entamide furoate
- Furamide
- Furamide (amebicide)
- Furentomin
- Furoic acid, ester with 2,2-dichloro-4′-hydroxy-N-methylacetanilide
- Histomibal
- Miforon
- Unii-Yp4N72Iw34
- Diloxanide furoate
- 2-furoicacid,esterwith2,2-dichloro-4’-hydroxy-n-methylacetanilide
- Diloxanide 2-furoic acid ester
- 2,2-DICHLORO-N-(4-HYDROXYPHENYL)-N-METHYLACETAMIDE 2-FUROIC ACID ESTER
- diloxanidfuroate
- entamidefuroate
- 2-furancarboxylicacid,4-((dichloroacetyl)methylamino)phenylester
- entamide2-furoate
- See more synonyms
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Found 9 products.
Diloxanide Furoate
CAS:Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereofFormula:C14H11Cl2NO4Color and Shape:White Off-White PowderMolecular weight:327.006512-Furancarboxylic acid, 4-[(dichloroacetyl)methylamino]phenyl ester
CAS:Formula:C14H11Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:328.1474Diloxanide furoate
CAS:Formula:C14H11Cl2NO4Purity:(Titration) ≥ 97.0%Color and Shape:White to off-white powder or crystalsMolecular weight:328.15Diloxanide furoate
CAS:Diloxanide furoate treats mild intestinal Amebiasis and is preferred for asymptomatic cyst carriers.Formula:C14H11Cl2NO4Purity:99.39%Color and Shape:SolidMolecular weight:328.15Diloxanide furoate
CAS:<p>Diloxanide furoate is a drug that belongs to the class of sulfa drugs. It is an amoebicidal agent that has been shown to be effective against Entamoeba histolytica, as well as other amoebae. Diloxanide furoate inhibits the enzyme polymerase chain reaction (PCR) in bacteria and eukaryotic cells, which prevents DNA replication and transcription. The mechanism of action for diloxanide furoate is similar to that of sulfonamides, with the exception that it does not inhibit dihydropteroate synthase like sulfonamides do. This drug also has minimal toxicity, which may be due to its low solubility in water and lack of absorption from the gastrointestinal tract.</p>Formula:C14H11Cl2NO4Purity:Min. 95%Color and Shape:PowderMolecular weight:328.15 g/mol
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