CAS 37364-66-2: Bleomycinic acid

Description:Bleomycinic acid, with the CAS number 37364-66-2, is a chemical compound that is a derivative of bleomycin, an antibiotic used primarily in cancer treatment. It is characterized by its complex structure, which includes a glycopeptide moiety and a unique metal-binding site that allows it to interact with DNA. This interaction leads to the formation of free radicals, resulting in DNA strand breaks, which is a key mechanism in its anticancer activity. Bleomycinic acid is typically less active than its parent compound, bleomycin, but it retains some biological properties. The compound is soluble in water and exhibits stability under physiological conditions, making it suitable for various pharmaceutical applications. Its use is primarily in the context of cancer therapy, where it is employed to target rapidly dividing cells. However, like many chemotherapeutic agents, it can have side effects, including pulmonary toxicity and skin reactions, necessitating careful monitoring during treatment. Overall, bleomycinic acid represents an important compound in the field of oncology and medicinal chemistry.

Formula:C₅₀H₇₂N₁₆O₂₂S₂

InChI:InChI=1S/C50H72N16O22S2/c1-15-28(63-41(66-39(15)53)20(7-26(52)70)58-8-19(51)40(54)76)44(79)65-30(36(21-9-56-14-59-21)86-49-38(34(74)32(72)24(10-67)85-49)87-48-35(75)37(88-50(55)83)33(73)25(11-68)84-48)45(80)60-17(3)31(71)16(2)42(77)64-29(18(4)69)43(78)57-6-5-27-61-22(12-89-27)46-62-23(13-90-46)47(81)82/h9,12-14,16-20,24-25,29-38,48-49,58,67-69,71-75H,5-8,10-11,51H2,1-4H3,(H2,52,70)(H2,54,76)(H2,55,83)(H,56,59)(H,57,78)(H,60,80)(H,64,77)(H,65,79)(H,81,82)(H2,53,63,66)

InChI key:InChIKey=MRNLLBXPSWMYCK-UHFFFAOYSA-N

SMILES:O=C(O)C=1N=C(SC1)C=2N=C(SC2)CCNC(=O)C(NC(=O)C(C)C(O)C(NC(=O)C(NC(=O)C=3N=C(N=C(N)C3C)C(NCC(N)C(=O)N)CC(=O)N)C(OC4OC(CO)C(O)C(O)C4OC5OC(CO)C(O)C(OC(=O)N)C5O)C6=CN=CN6)C)C(O)C

Synonyms:
Bleomycinic acid
Bleomycin acid
See more synonyms

Found 3 products.

Product data	Purity	Price range	Estimated delivery
Bleomycin Acid REF: 4Z-B-190003CAS: 37364-66-2	- - -	To inquire	Fri 09 May 25
Bleomycin Acid REF: TR-B595810CAS: 37364-66-2	- - -	3,919.00 €	Thu 12 Jun 25
Bleomycin acid REF: 3D-MBA36466CAS: 37364-66-2	Min. 95%	3,460.00 €~5,767.00 €	Fri 13 Jun 25