CAS 37385-92-5

5-chloro-1-methyl-3-phenyl-1,3-dihydro-2H-benzimidazol-2-one

Description:

5-Chloro-1-methyl-3-phenyl-1,3-dihydro-2H-benzimidazol-2-one is a chemical compound characterized by its unique structure, which includes a benzimidazole core substituted with a chlorine atom, a methyl group, and a phenyl group. This compound typically exhibits properties associated with heterocyclic compounds, including potential biological activity due to its structural features. It may display moderate solubility in organic solvents and limited solubility in water, which is common for many benzimidazole derivatives. The presence of the chlorine atom can influence its reactivity and interaction with biological targets, potentially enhancing its pharmacological properties. Additionally, the compound may exhibit fluorescence, making it useful in various applications, including medicinal chemistry and material science. Its synthesis and characterization would involve standard organic chemistry techniques, and it may serve as a precursor or intermediate in the development of pharmaceuticals or agrochemicals. As with many chemical substances, safety data sheets should be consulted for handling and toxicity information.

Formula: C₁₄H₁₁ClN₂O

InChI: InChI=1/C14H11ClN2O/c1-16-12-8-7-10(15)9-13(12)17(14(16)18)11-5-3-2-4-6-11/h2-9H,1H3

SMILES: Cn1c2ccc(cc2n(c2ccccc2)c1=O)Cl

Clobazam Impurity 12

CAS: 37385-92-5

Formula: C₁₄H₁₁ClN₂O

Molecular weight: 258.71

Ref: 4Z-C-235034

5-Chloro-1,3-dihydro-1-methyl-3-phenyl-2H-benzimidazol-2-one

Controlled Product

CAS: 37385-92-5

Applications 5-Chloro-1,3-dihydro-1-methyl-3-phenyl-2H-benzimidazol-2-one is an intermediate in the synthesis of Clobazam (C582500), a benzodiazepine psychotherapeutic agent and anxiolytic agent.
References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993),

Formula: C₁₄H₁₁ClN₂O

Color and Shape: Neat

Molecular weight: 258.7

Ref: TR-C371190

5-Chloro-1,3-dihydro-1-methyl-3-phenyl-2H-benzimidazol-2-one-d5

Controlled Product

CAS: 37385-92-5

Formula: C₁₄D₅H₆ClN₂O

Color and Shape: Neat

Molecular weight: 263.734

Ref: TR-C371192

5-Chloro-1,3-dihydro-1-methyl-3-phenyl-2H-benzimidazol-2-one-d5

CAS: 37385-92-5

5-Chloro-1,3-dihydro-1-methyl-3-phenyl-2H-benzimidazol-2-one is a synthetic impurity that may be found in drug products. It is used as an analytical standard and is metabolized to 5,5'-dichloroquinoline by hydrolysis of the acetal linkage. The metabolite 5,5'-dichloroquinoline has been shown to have antiplatelet effects in vitro and may contribute to the antithrombotic activity of the parent compound. This substance is not intended for clinical use.

Formula: C₁₄H₁₁ClN₂O

Purity: Min. 95%

Molecular weight: 258.7 g/mol

Ref: 3D-MBA38592

Clobazam Impurity 3

CAS: 37385-92-5

Formula: C₁₄H₁₁ClN₂O

Molecular weight: 258.7

Ref: ST-EA-CP-C28013