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CAS 37415-57-9

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Deoxyphorbol

Description:
Deoxyphorbol is a chemical compound classified as a phorbol ester, which is derived from the sap of the croton plant. It is known for its role in biological research, particularly in studies related to tumor promotion and signal transduction pathways. Deoxyphorbol exhibits a structure that allows it to interact with protein kinase C (PKC), a family of enzymes that play crucial roles in various cellular processes, including growth, differentiation, and apoptosis. The compound is typically characterized by its lipophilic nature, which facilitates its ability to penetrate cell membranes. Deoxyphorbol is often used in laboratory settings to investigate the mechanisms of cancer development and the effects of phorbol esters on cellular signaling. Its biological activity can vary depending on the specific context and concentration used in experiments. As with many phorbol esters, caution is advised when handling deoxyphorbol due to its potential biological effects and toxicity.
Formula:C20H28O5
Synonyms:
  • 4-deoxy-4-Phorbol
  • (1aR)-1,1aα,1bβ,4,4aα,7aα,7b,8,9,9a-Decahydro-7bα,9β,9aα-trihydroxy-3-hydroxymethyl-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one
  • Deoxyphorbol
  • 4-deoxy-4α-Phorbol
  • (1aR)-1,1,6,8α-Tetramethyl-3-(hydroxymethyl)-7bα,9β,9aα-trihydroxy-1,1aα,1bβ,4,4aα,7aα,7b,8,9,9a-decahydro-5H-cyclopropa[3,4]benzo[1,2-e]azulene-5-one
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