CAS 37517-26-3

Pipotiazine palmitate

Description:

Pipotiazine palmitate is a chemical compound classified as an antipsychotic medication, primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the thienobenzodiazepine class and exhibits properties that help in managing symptoms such as hallucinations and delusions. The substance is characterized by its ability to act as a dopamine receptor antagonist, which is crucial for its therapeutic effects. Pipotiazine palmitate is typically administered via intramuscular injection, allowing for prolonged release and sustained therapeutic levels in the body. Its pharmacokinetics involve a gradual absorption and a long half-life, which contributes to its efficacy in long-term treatment regimens. Additionally, it may have sedative effects, which can be beneficial in managing agitation associated with psychotic episodes. As with many antipsychotic medications, potential side effects may include weight gain, sedation, and extrapyramidal symptoms, necessitating careful monitoring during treatment. Overall, pipotiazine palmitate is an important option in the pharmacological management of severe mental health disorders.

Formula: C₄₀H₆₃N₃O₄S₂

InChI: InChI=1S/C40H63N3O4S2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-22-40(44)47-32-27-34-25-30-42(31-26-34)28-19-29-43-36-20-17-18-21-38(36)48-39-24-23-35(33-37(39)43)49(45,46)41(2)3/h17-18,20-21,23-24,33-34H,4-16,19,22,25-32H2,1-3H3

InChI key: InChIKey=KTOYYUONFQWSMW-UHFFFAOYSA-N

SMILES: C(CCN1CCC(CCOC(CCCCCCCCCCCCCCC)=O)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3

Synonyms:

• 10-(3-(4-(2-Hydroxyethyl)piperidino)propyl)-N,N-dimethylphenothiazine-2-sulfonamide palmitate (ester)
• 2-(1-{3-[2-(dimethylsulfamoyl)-10H-phenothiazin-10-yl]propyl}piperidin-4-yl)ethyl hexadecanoate
• Hexadecanoic acid, 2-(1-(3-(2-((dimethylamino)sulfonyl)-10H-phenothiazin-10-yl)propyl)-4-piperidinyl)ethyl ester
• Il 19552
• Piportil L 4
• Pipothiazine palmitate
• Pipotiazine palmitate
• Pipotiazine palmitate [USAN]
• Pipotiazine palmitic ester
• Rp 19552
• Unii-4Q3H01Qrmi

Pipotiazine Palmitate

CAS: 37517-26-3

Formula: C₄₀H₆₃N₃O₄S₂

Color and Shape: Light Yellow Solid

Molecular weight: 714.08

Ref: 4Z-P-289002

Pipotiazine

Controlled Product

CAS: 37517-26-3

Formula: C₄₀H₆₃N₃O₄S₂

Color and Shape: Neat

Molecular weight: 714.08

Ref: TR-P398605

Pipotiazine Palmitate

CAS: 37517-26-3

Formula: C₄₀H₆₃N₃O₄S₂

Color and Shape: Off White Solid

Molecular weight: 714.08

Ref: TR-P490700

Pipotiazine palmitate

Controlled Product

CAS: 37517-26-3

Pipotiazine palmitate is a long-acting antipsychotic drug that belongs to the class of phenothiazine derivatives. It is used for the treatment of schizophrenia and other psychotic disorders. Pipotiazine palmitate has been shown to be effective in treating chronic schizophrenia with minimal side effects. This drug binds to dopamine D2 receptors, which leads to a decrease in dopaminergic activity in the brain and improves symptoms of psychosis. Pipotiazine palmitate is administered orally in two doses per day. A major limitation of this medication is its low bioavailability due to its high lipophilicity, which may be due to its undecylenate ester form.

Formula: C₄₀H₆₃N₃O₄S₂

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 714.08 g/mol

Ref: 3D-FP27077