CAS 37517-81-0

Methyl 3-chloro-3-oxopropanoate

Description:

Methyl 3-chloro-3-oxopropanoate is an organic compound characterized by its ester functional group, which is derived from propanoic acid. It features a chloro substituent and a keto group, contributing to its reactivity and potential applications in organic synthesis. The presence of the chlorine atom enhances its electrophilic character, making it useful in various chemical reactions, such as nucleophilic substitutions. This compound is typically a colorless to pale yellow liquid with a distinctive odor. It is soluble in organic solvents and may have limited solubility in water due to its hydrophobic ester group. Methyl 3-chloro-3-oxopropanoate can be utilized in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. As with many chlorinated compounds, it is important to handle it with care, as it may pose health and environmental risks. Proper safety measures should be observed when working with this substance, including the use of personal protective equipment and adherence to relevant regulations regarding chemical handling and disposal.

Formula: C₄H₅ClO₃

InChI: InChI=1S/C4H5ClO3/c1-8-4(7)2-3(5)6/h2H2,1H3

InChI key: InChIKey=UTBCRHAMJFMIIR-UHFFFAOYSA-N

SMILES: C(CC(Cl)=O)(OC)=O

Synonyms:

• (Carbomethoxy)acetyl chloride
• (Methoxycarbonyl)acetyl chloride
• 2-Methoxycarbonylacetyl chloride
• 3-Chloro-3-oxopropanoic acid methyl ester
• 3-Methoxy-3-oxopropanoyl chloride
• Aurora Ka-3053
• Chlorocarbonylacetic acid methyl ester
• Malonic acid chloride monomethyl ester
• Malonic acid monomethyl ester chloride
• Mehtyl Malonyl Chloride
• Methyl (chlorocarbonyl)acetate
• Methyl (chloroformyl)acetate
• Methyl 2-(chlorocarbonyl)acetate
• Methyl 2-(chloroformyl)acetate
• Methyl 3-Chloro-3-Oxopropanoate
• Methyl 3-chloro-3-oxopropionate
• Methyl chloroformylacetate
• Propanoic acid, 3-chloro-3-oxo-, methyl ester

Methyl Malonyl Chloride

CAS: 37517-81-0

Formula: C₄H₅ClO₃

Purity: >97.0%(GC)(T)

Color and Shape: Colorless to Yellow to Orange clear liquid

Molecular weight: 136.53

Ref: 3B-M2315

Methyl malonyl chloride, 97%

CAS: 37517-81-0

Methyl malonyl chloride is used as pharmaceutical intermediate. Used in anti-cancer drugs. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product /

Formula: C₄H₅ClO₃

Purity: 97%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 136.53

Ref: 02-020823

Methyl 3-chloro-3-oxopropanoate

CAS: 37517-81-0

Formula: C₄H₅ClO₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 136.5337

Ref: IN-DA00356S

Methyl malonyl chloride

CAS: 37517-81-0

Methyl malonyl chloride

Formula: C₄H₅ClO₃

Purity: 96%

Color and Shape: clear. light yellow liquid

Molecular weight: 136.53g/mol

Ref: 54-OR8845

Methyl malonyl chloride

CAS: 37517-81-0

Formula: C₄H₅ClO₃

Purity: 95.0%

Color and Shape: Clear

Molecular weight: 136.53

Ref: 10-F013167

Ethyl Malonyl Chloride

CAS: 37517-81-0

Formula: C₄H₅ClO₃

Molecular weight: 136.53

Ref: 4Z-M-213003

Methyl 3-Chloro-3-oxopropionate

Controlled Product

CAS: 37517-81-0

Applications Methyl 3-chloro-3-oxopropionate is a reagent that is used in the synthesis of pyrrolopiperidinone acetic acids as CRTh2 antagonists/
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Andres, M., et al.: Bioorg. Med. Chem. Lett., 24, 5111 (2014);

Formula: C₄H₅ClO₃

Color and Shape: Neat

Molecular weight: 136.53

Ref: TR-M316740

Methyl malonyl chloride

CAS: 37517-81-0

Methyl malonyl chloride is an experimental solubility data that is soluble in benzene, toluene, and chloroform. It has been shown to have a receptor activity towards the glycol ester and natural compounds. This compound has also been found to inhibit cervical cancer cells. Methyl malonyl chloride is used as an antimicrobial agent in the food industry and can be used as a natural growth factor inhibitor. The methyl group of this compound reacts with malonic acid to form methylmalonic acid, which inhibits mitochondrial membrane potential in cancer cells.

Formula: C₄H₅ClO₃

Purity: Min. 95%

Molecular weight: 136.53 g/mol

Ref: 3D-FM60071