Bertilimumab is a monoclonal antibody that targets the chemokine receptor CCR2, which plays a significant role in inflammatory processes and immune responses. It is primarily investigated for its potential therapeutic applications in autoimmune diseases and conditions characterized by chronic inflammation. The mechanism of action involves blocking the interaction between CCR2 and its ligands, thereby inhibiting the recruitment of inflammatory cells to sites of tissue damage. This action may help reduce inflammation and tissue injury in various diseases. Bertilimumab has undergone clinical trials to assess its efficacy and safety profile in conditions such as ulcerative colitis and other inflammatory disorders. As a biologic agent, it is produced through recombinant DNA technology and typically administered via injection. The development of Bertilimumab reflects the growing interest in targeted therapies that modulate specific pathways in the immune system, offering a more tailored approach to treatment compared to traditional systemic therapies.

Bertilimumab

375348-49-5: Bertilimumab is a monoclonal antibody that targets the chemokine receptor CCR2, which plays a significant role in inflammatory processes and immune responses. It is primarily investigated for its potential therapeutic applications in autoimmune diseases and conditions characterized by chronic inflammation. The mechanism of action involves blocking the interaction between CCR2 and its ligands, thereby inhibiting the recruitment of inflammatory cells to sites of tissue damage. This action may help reduce inflammation and tissue injury in various diseases. Bertilimumab has undergone clinical trials to assess its efficacy and safety profile in conditions such as ulcerative colitis and other inflammatory disorders. As a biologic agent, it is produced through recombinant DNA technology and typically administered via injection. The development of Bertilimumab reflects the growing interest in targeted therapies that modulate specific pathways in the immune system, offering a more tailored approach to treatment compared to traditional systemic therapies.

<p>Bertilimumab (CAT 213; iCo-008), a human monoclonal antibody that targets eotaxin-1 (CCL11), shows promise in the research of allergic disorders [1].</p>

<p>Human monoclonal antibody targeting CCL11 (ecotaxin-1); allergy disorders</p>

CAS 375348-49-5

Bertilimumab

Bertilimumab

Ref: TM-T76928

Bertilimumab

Ref: 3D-CLA1138