CAS 37552-33-3

des-gly nh29,-arg8-vasopressin

Description:

Des-gly-NH2-Arg8-vasopressin, also known as desmopressin, is a synthetic analog of the natural hormone vasopressin, which is involved in regulating water retention in the body and blood pressure. This compound is characterized by its modified structure, where the glycine residue at the first position is replaced with an amine group, and the arginine at the eighth position is retained, enhancing its antidiuretic properties. Desmopressin is primarily used in clinical settings to treat conditions such as diabetes insipidus and certain bleeding disorders, including von Willebrand disease and hemophilia A, due to its ability to increase the levels of clotting factors and promote water reabsorption in the kidneys. The compound is typically administered via intranasal or intravenous routes, and it exhibits a longer duration of action compared to natural vasopressin, making it effective for therapeutic use. Its safety profile is generally favorable, although potential side effects may include headache, nausea, and changes in blood pressure.

Formula: C₄₄H₆₁N₁₃O₁₂S₂

InChI: InChI=1/C44H61N13O12S2/c45-26-21-70-71-22-32(42(67)57-17-5-9-33(57)41(66)52-28(43(68)69)8-4-16-50-44(48)49)56-40(65)31(20-35(47)60)55-37(62)27(14-15-34(46)59)51-38(63)30(18-23-6-2-1-3-7-23)54-39(64)29(53-36(26)61)19-24-10-12-25(58)13-11-24/h1-3,6-7,10-13,26-33,58H,4-5,8-9,14-22,45H2,(H2,46,59)(H2,47,60)(H,51,63)(H,52,66)(H,53,61)(H,54,64)(H,55,62)(H,56,65)(H,68,69)(H4,48,49,50)/t26-,27-,28-,29-,30+,31-,32?,33?/m0/s1

Synonyms:

• Argipressin, des-glynh2(9)-
• (Arg8,de-Gly9)-vasopressin
• (Deglycinamide9,arginine8)-vasopressin
• (Desglycinamide9-arginine8)-vasopressin
• (arg8,des-Gly-NH29)-vasopressin
• 8-Arg-9-des-gly-vasopressin dicitrate salt
• 8-Arginine-9-deglycinamide-vasopressin
• 8-Arginine-9-desglycinamide vasopressin
• 9-Deglycinamide-argipressin
• 9-Des-glynh2-argipressin
• Arginine vasopressin, des-glynh2(9)-
• Arginine vasopression-(1-8)
• Argipressin, de-glycinamide(9)-
• Argipressin, desglycinamide(9)-
• Deavp
• Dgavp
• Org 5667
• Vasopressin, 8-L-arginine-9-deglycinamide-
• 1-8-Vasopressin, 8-L-arginine-

(Arg⁸,des-Gly-NH₂⁹)-Vasopressin

CAS: 37552-33-3

Bachem ID: 4031337.

Formula: C₄₄H₆₁N₁₃O₁₂S₂

Color and Shape: White Powder

Molecular weight: 1028.18

Ref: 01-4031337

Argipressin, des-glynh2(9)-

CAS: 37552-33-3

Argipressin, des-glynh2(9)-, can effect on aggregation of blood platelets.

Formula: C₄₄H₆₁N₁₃O₁₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1028.17

Ref: TM-TP2450

Des Gly9 NH2-Vasopressin

CAS: 37552-33-3

Formula: C₄₄H₆₁N₁₃O₁₂S₂

Molecular weight: 1028.17

Ref: ST-EA-CP-V42006

(Arg8,des-Gly-NH29)-Vasopressin

CAS: 37552-33-3

Vasopressin is a hormone that is released from the posterior pituitary gland and stimulates the release of water from the kidneys. Vasopressin binds to receptors in the kidney tubules and increases water permeability and urine volume. Vasopressin also has been shown to be effective in reducing sensitivity to ionizing radiation, which may be due to its ability to bind with sulfur-containing amino acids such as cysteine and glutathione. The radiolabeled form of vasopressin is used as a tracer for measuring lung function, including volumes of air flow, gas density, and gas volume.

Formula: C₄₄H₆₁N₁₃O₁₂S₂

Purity: Min. 95%

Molecular weight: 1,028.17 g/mol

Ref: 3D-FA108913