The chemical substance known as H-Phe-Pro-Arg-OH, with the CAS number 37553-80-3, is a peptide that consists of three amino acids: phenylalanine (Phe), proline (Pro), and arginine (Arg). This compound is characterized by its specific sequence of amino acids, which contributes to its biological activity and potential applications in biochemical research and therapeutic contexts. The "H-" prefix indicates that the peptide is in its free acid form, while the "OH" at the end signifies the presence of a carboxylic acid group. Peptides like H-Phe-Pro-Arg-OH are often studied for their roles in signaling pathways, their potential as hormone analogs, or their use in drug development. The presence of the arginine residue may impart positive charge and enhance interactions with biological targets, while proline can introduce structural rigidity. Overall, this peptide's unique sequence and functional groups make it a subject of interest in various fields, including pharmacology and molecular biology.

H-Phe-Pro-Arg-OH

37553-80-3: The chemical substance known as H-Phe-Pro-Arg-OH, with the CAS number 37553-80-3, is a peptide that consists of three amino acids: phenylalanine (Phe), proline (Pro), and arginine (Arg). This compound is characterized by its specific sequence of amino acids, which contributes to its biological activity and potential applications in biochemical research and therapeutic contexts. The "H-" prefix indicates that the peptide is in its free acid form, while the "OH" at the end signifies the presence of a carboxylic acid group. Peptides like H-Phe-Pro-Arg-OH are often studied for their roles in signaling pathways, their potential as hormone analogs, or their use in drug development. The presence of the arginine residue may impart positive charge and enhance interactions with biological targets, while proline can introduce structural rigidity. Overall, this peptide's unique sequence and functional groups make it a subject of interest in various fields, including pharmacology and molecular biology.

<p>H-Phe-Pro-Arg-OH is an active analogue of the natural amino acid, lysine. It has been shown to inhibit protein synthesis by binding to the lysine residues in proteins. This inhibition blocks the hydrophobic effect that is necessary for proper folding of newly synthesized proteins. Lysine's role in protein synthesis also extends to spermatozoa and blood clotting, which are inhibited by H-Phe-Pro-Arg-OH. The inhibition of lysine residues in human serum fibrinogen and thrombin may lead to a reduction in their ability to form clots. H-Phe-Pro-Arg-OH has also been shown to be an anticoagulant and thermodynamic data supports this conclusion. X ray crystal structures and titration calorimetry have confirmed that this compound binds to lysine residues with high affinity and specificity.</p>

CAS 37553-80-3

H-Phe-Pro-Arg-OH

H-Phe-Pro-Arg-OH

Ref: 3D-FP109121