CAS 37558-16-0: phorbol 12,13-dibutyrate

Description: Phorbol 12,13-dibutyrate (PDBu) is a synthetic phorbol ester derived from the natural compound phorbol, which is obtained from the resin of the Euphorbia plant. It is characterized by its ability to act as a potent tumor promoter and a protein kinase C (PKC) activator, making it a valuable tool in cancer research and cell signaling studies. PDBu is a lipophilic compound, which allows it to easily penetrate cell membranes and interact with cellular targets. Its structure includes two butyrate groups esterified to the phorbol backbone, enhancing its biological activity compared to other phorbol esters. PDBu is often used in laboratory settings to induce differentiation in various cell types and to study the mechanisms of signal transduction. Additionally, it has been shown to influence various cellular processes, including proliferation, apoptosis, and gene expression. Due to its potent biological effects, PDBu is handled with care in research environments, and its use is subject to regulatory guidelines.

Formula: C₂₈H₄₀O₈

InChI: InChI=1S/C28H40O8/c1-7-9-20(30)35-24-16(4)27(34)18(22-25(5,6)28(22,24)36-21(31)10-8-2)12-17(14-29)13-26(33)19(27)11-15(3)23(26)32/h11-12,16,18-19,22,24,29,33-34H,7-10,13-14H2,1-6H3/t16-,18+,19-,22-,24-,26-,27-,28-/m1/s1

InChI key: InChIKey=BQJRUJTZSGYBEZ-YVQNUNKESA-N

SMILES: O=C(OC1C(C)C2(O)C(C=C(CO)CC3(O)C(=O)C(=CC32)C)C4C1(OC(=O)CCC)C4(C)C)CCC

Synonyms:

• (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl dibutanoate
• 12,13-Di-O-butyrylphorbol
• 4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl dibutanoate
• 4β-Phorbol 12,13-dibutyrate
• 9aH-Cyclopropa[3,4]benz[1,2-e]azulene, butanoic acid deriv.
• Butanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester
• Butanoic acid, 1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl ester, [1aR-(1aα,1bβ,4aβ,7aα,7bα,8α,9β,9aα)]-
• Butanoic acid, 1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester, (1aR-(1a-alpha,1b-beta,4a-beta,7a-alpha,7b-alpha,8-alpha,9-beta,9a-alpha))-
• Nsc 622507
• Phorbol dibutyrate

PHORBOL 12,13-DIBUTYRATE

CAS: 37558-16-0

• Formula: C₂₈H₄₀O₈
• Purity: 100%
• Molecular weight: 504.6124

Phorbol 12,13-dibutyrate

CAS: 37558-16-0

• Formula: C₂₈H₄₀O₈
• Molecular weight: 504.61

Phorbol 12,13-Dibutyrate

CAS: 37558-16-0

• Formula: C₂₈H₄₀O₈
• Purity: >99%
• Color and Shape: solid
• Molecular weight: 504.61g/mol

Phorbol 12,13-dibutyrate

CAS: 37558-16-0

Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular …

• Formula: C₂₈H₄₀O₈
• Purity: 100% - 99.32%
• Color and Shape: Solid
• Molecular weight: 504.61

Phorbol 12,13-dibutyrate

CAS: 37558-16-0

Please enquire for more information about Phorbol 12,13-dibutyrate including the price, delivery time and more …

• Formula: C₂₈H₄₀O₈
• Purity: Min. 95 Area-%
• Color and Shape: Powder
• Molecular weight: 504.61 g/mol