CAS 37561-27-6

Fenoverine

Description:

Fenoverine is a pharmaceutical compound primarily used as an antispasmodic agent. It is characterized by its ability to relieve smooth muscle spasms, particularly in the gastrointestinal tract. The substance is often utilized in the treatment of conditions such as irritable bowel syndrome and other digestive disorders. Fenoverine functions by inhibiting the contraction of smooth muscle, thereby alleviating pain and discomfort associated with spasms. Its chemical structure includes a phenyl group, which contributes to its pharmacological properties. The compound is typically administered in oral form and is well-absorbed in the gastrointestinal system. Side effects may include gastrointestinal disturbances or allergic reactions, although these are generally mild. As with any medication, it is essential to use Fenoverine under the guidance of a healthcare professional to ensure safety and efficacy. Overall, Fenoverine represents a valuable option in the management of spastic gastrointestinal conditions, providing symptomatic relief for patients.

Formula: C₂₆H₂₅N₃O₃S

InChI: InChI=1S/C26H25N3O3S/c30-26(29-20-5-1-3-7-24(20)33-25-8-4-2-6-21(25)29)17-28-13-11-27(12-14-28)16-19-9-10-22-23(15-19)32-18-31-22/h1-10,15H,11-14,16-18H2

InChI key: InChIKey=UBAJTZKNDCEGKL-UHFFFAOYSA-N

SMILES: C(CN1CCN(CC=2C=C3C(=CC2)OCO3)CC1)(=O)N4C=5C(SC=6C4=CC=CC6)=CC=CC5

Synonyms:

• 10-((4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl)acetyl)-10H-phenothiazine
• 10-((4-Piperonyl-1-piperazinyl)acetyl)phenothiazine
• 10H-Phenothiazine, 10-((4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)acetyl)-
• 2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-1-phenothiazin-10-yl-ethanone
• 2-[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]-1-(10H-phenothiazin-10-yl)ethanone
• 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-(10H-phenothiazin-10-yl)ethanone
• Ethanone, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-(10H-phenothiazin-10-yl)-
• Fenoverina
• Fenoverina [INN-Spanish]
• Fenoverine [INN:DCF]
• Fenoverinum
• Fenoverinum [INN-Latin]
• Spasmopriv
• Unii-N274Zq6Pzj

Fenoverine

CAS: 37561-27-6

Fenoverine

Purity: ≥98%

Molecular weight: 459.56g/mol

Ref: 54-BUP14185

Fenoverine

CAS: 37561-27-6

Formula: C₂₆H₂₅N₃O₃S

Molecular weight: 459.56

Ref: 4Z-F-135001

Fenoverine

Controlled Product

CAS: 37561-27-6

Applications Fenoverine is a colon-specific multi particulate drug. Also, it is an antispasmodic drug which inhibits contraction of smooth muscle. It is derived from Phenothiazine (P318040), which is a key component of antipsychotic and antihistaminic drugs.
References Diddi, S., et al.: Int. J. Pharm. Pharm. Sci., 6, 227-231 (2014); Deodhar, P., et al.: J. Pharm. Res., 5, 3406-3409 (2012); Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009), Baell, J., et al.: J. Med. Chem., 53, 2719 (2010), Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010), Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010), Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010);

Formula: C₂₆H₂₅N₃O₃S

Color and Shape: Off-White To Beige

Molecular weight: 459.56

Ref: TR-F248898

Fenoverine

CAS: 37561-27-6

Fenoverine (Spasmopriv) has antispasmodic activity and can be used to study gastrointestinal spasms.

Formula: C₂₆H₂₅N₃O₃S

Purity: 98.34%

Color and Shape: Solid

Molecular weight: 459.56

Ref: TM-T62889