CAS 37566-40-8

5-Chloro-1,3,4-thiadiazol-2-amine

Description:

5-Chloro-1,3,4-thiadiazol-2-amine is a heterocyclic compound characterized by the presence of a thiadiazole ring, which contains both sulfur and nitrogen atoms. This compound features a chlorine substituent at the 5-position and an amino group at the 2-position of the thiadiazole ring. It is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the amino group, which can engage in hydrogen bonding. The compound is of interest in various fields, including medicinal chemistry and agrochemicals, due to its potential biological activity and utility as a building block in the synthesis of more complex molecules. Its reactivity can be influenced by the electron-withdrawing nature of the chlorine atom and the electron-donating properties of the amino group, making it a versatile intermediate in organic synthesis. Safety data should be consulted for handling, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₂H₂ClN₃S

InChI: InChI=1S/C2H2ClN3S/c3-1-5-6-2(4)7-1/h(H2,4,6)

InChI key: InChIKey=OPGJORQBYBKWNH-UHFFFAOYSA-N

SMILES: ClC=1SC(N)=NN1

Synonyms:

• 1,3,4-Thiadiazol-2-Amine, 5-Chloro-
• 2-Amino-5-chloro-1,3,4-thiadiazole
• NSC 231514
• 5-Chloro-1,3,4-thiadiazol-2-amine
• 5-Chloro-1,3,4-thiadiazol-2-amine

5-Chloro-1,3,4-thiadiazol-2-ylamine

CAS: 37566-40-8

Formula: C₂H₂ClN₃S

Purity: 96%

Color and Shape: Solid

Molecular weight: 135.5754

Ref: IN-DA00C9YX

5-Chloro-1,3,4-thiadiazol-2-amine

CAS: 37566-40-8

5-Chloro-1,3,4-thiadiazol-2-amine

Purity: 97%

Molecular weight: 135.58g/mol

Ref: 54-OR1011844

5-Chloro-1,3,4-thiadiazol-2-ylamine

CAS: 37566-40-8

Formula: C₂H₂ClN₃S

Purity: 96%

Color and Shape: Solid

Molecular weight: 135.57

Ref: 10-F079734

5-Chloro-1,3,4-thiadiazol-2-amine

Controlled Product

CAS: 37566-40-8

Applications 5-Chloro-1,3,4-thiadiazol-2-amine was found to be active against several transplanted animal tumors. It can also be used to synthesize 6-fluoro-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-ones.
References Oleson, J., et al.: J. Am. Chem. Soc., 77, 6713 (1955); Kukaniev, M., et al: J. Heterocyclic. Chem., 48, 1308 (2011)

Formula: C₂H₂ClN₃S

Color and Shape: Neat

Molecular weight: 135.58

Ref: TR-C411460